Distillation-Driven Diffusion Model for Multi-Scale MRI Super-Resolution: Make 1.5T MRI Great Again

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Main Authors: Wang, Zhe, Ru, Yuhua, Bauer, Fabian, Chetouani, Aladine, Chen, Fang, Zhang, Liping, Hans, Didier, Jennane, Rachid, Jarraya, Mohamed, Chen, Yung Hsin
Format: Preprint
Published: 2025
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author Wang, Zhe
Ru, Yuhua
Bauer, Fabian
Chetouani, Aladine
Chen, Fang
Zhang, Liping
Hans, Didier
Jennane, Rachid
Jarraya, Mohamed
Chen, Yung Hsin
author_facet Wang, Zhe
Ru, Yuhua
Bauer, Fabian
Chetouani, Aladine
Chen, Fang
Zhang, Liping
Hans, Didier
Jennane, Rachid
Jarraya, Mohamed
Chen, Yung Hsin
contents Magnetic Resonance Imaging (MRI) offers critical insights into microstructural details, however, the spatial resolution of standard 1.5T imaging systems is often limited. In contrast, 7T MRI provides significantly enhanced spatial resolution, enabling finer visualization of anatomical structures. Though this, the high cost and limited availability of 7T MRI hinder its widespread use in clinical settings. To address this challenge, a novel Super-Resolution (SR) model is proposed to generate 7T-like MRI from standard 1.5T MRI scans. Our approach leverages a diffusion-based architecture, incorporating gradient nonlinearity correction and bias field correction data from 7T imaging as guidance. Moreover, to improve deployability, a progressive distillation strategy is introduced. Specifically, the student model refines the 7T SR task with steps, leveraging feature maps from the inference phase of the teacher model as guidance, aiming to allow the student model to achieve progressively 7T SR performance with a smaller, deployable model size. Experimental results demonstrate that our baseline teacher model achieves state-of-the-art SR performance. The student model, while lightweight, sacrifices minimal performance. Furthermore, the student model is capable of accepting MRI inputs at varying resolutions without the need for retraining, significantly further enhancing deployment flexibility. The clinical relevance of our proposed method is validated using clinical data from Massachusetts General Hospital. Our code is available at https://github.com/ZWang78/SR.
format Preprint
id arxiv_https___arxiv_org_abs_2501_18736
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Distillation-Driven Diffusion Model for Multi-Scale MRI Super-Resolution: Make 1.5T MRI Great Again
Wang, Zhe
Ru, Yuhua
Bauer, Fabian
Chetouani, Aladine
Chen, Fang
Zhang, Liping
Hans, Didier
Jennane, Rachid
Jarraya, Mohamed
Chen, Yung Hsin
Image and Video Processing
Computer Vision and Pattern Recognition
Magnetic Resonance Imaging (MRI) offers critical insights into microstructural details, however, the spatial resolution of standard 1.5T imaging systems is often limited. In contrast, 7T MRI provides significantly enhanced spatial resolution, enabling finer visualization of anatomical structures. Though this, the high cost and limited availability of 7T MRI hinder its widespread use in clinical settings. To address this challenge, a novel Super-Resolution (SR) model is proposed to generate 7T-like MRI from standard 1.5T MRI scans. Our approach leverages a diffusion-based architecture, incorporating gradient nonlinearity correction and bias field correction data from 7T imaging as guidance. Moreover, to improve deployability, a progressive distillation strategy is introduced. Specifically, the student model refines the 7T SR task with steps, leveraging feature maps from the inference phase of the teacher model as guidance, aiming to allow the student model to achieve progressively 7T SR performance with a smaller, deployable model size. Experimental results demonstrate that our baseline teacher model achieves state-of-the-art SR performance. The student model, while lightweight, sacrifices minimal performance. Furthermore, the student model is capable of accepting MRI inputs at varying resolutions without the need for retraining, significantly further enhancing deployment flexibility. The clinical relevance of our proposed method is validated using clinical data from Massachusetts General Hospital. Our code is available at https://github.com/ZWang78/SR.
title Distillation-Driven Diffusion Model for Multi-Scale MRI Super-Resolution: Make 1.5T MRI Great Again
topic Image and Video Processing
Computer Vision and Pattern Recognition
url https://arxiv.org/abs/2501.18736