Effect of a new type of healthy and live food supplement on osteoporosis blood parameters and induced rheumatoid arthritis in Wistar rats

Fuente: arXiv
Guardado en:
Detalles Bibliográficos
Autores principales: Bayat, Azam, Khalkhali, Aref, Mahjoub, Ali Reza
Formato: Preprint
Publicado: 2025
Materias:
Acceso en línea:
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
_version_ 1866929693249241088
author Bayat, Azam
Khalkhali, Aref
Mahjoub, Ali Reza
author_facet Bayat, Azam
Khalkhali, Aref
Mahjoub, Ali Reza
contents Summary Osteoporosis is a skeletal disorder, characterized by a decrease in bone strength and puts the individual at risk for fracture. On the other hand, rheumatoid arthritis is a systemic disease of unknown etiology that causes inflammation of the joints of the organs. Purpose Due to the destructive effects of these diseases and its increasing prevalence and lack of appropriate medication for treatment, the present study aimed to evaluate the therapeutic effect of a new type of healthy and live food supplement on rheumatoid arthritis and induced osteoporosis in rats. Methods In this research, healthy and live food powder were synthesized by a new and green route. This organic biomaterial was named NBS. The NBS food supplement had various vitamins, macro and micro molecules, and ingredients. The new healthy and nutritious diet showed that the use of this supplement led to the return of the parameters to normal levels. Results The concentration of 12.5 mg/ kg showed the least therapeutic effect and 50 mg/ kg had the highest therapeutic effect for osteoporosis. The results of blood parameters involved in inflammation in both healthy and patient groups showed that the use of complete adjuvant induction causes joint inflammation. In the study of the interaction of the concentrations, it was observed that the concentration of 50 mg/ kg had the highest therapeutic effect against the disease in the studied mice. Conclusion The results showed that the new healthy and viable supplement restores the blood osteoporotic and rheumatoid factors of the mice to normal.
format Preprint
id arxiv_https___arxiv_org_abs_2501_19343
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Effect of a new type of healthy and live food supplement on osteoporosis blood parameters and induced rheumatoid arthritis in Wistar rats
Bayat, Azam
Khalkhali, Aref
Mahjoub, Ali Reza
Tissues and Organs
Summary Osteoporosis is a skeletal disorder, characterized by a decrease in bone strength and puts the individual at risk for fracture. On the other hand, rheumatoid arthritis is a systemic disease of unknown etiology that causes inflammation of the joints of the organs. Purpose Due to the destructive effects of these diseases and its increasing prevalence and lack of appropriate medication for treatment, the present study aimed to evaluate the therapeutic effect of a new type of healthy and live food supplement on rheumatoid arthritis and induced osteoporosis in rats. Methods In this research, healthy and live food powder were synthesized by a new and green route. This organic biomaterial was named NBS. The NBS food supplement had various vitamins, macro and micro molecules, and ingredients. The new healthy and nutritious diet showed that the use of this supplement led to the return of the parameters to normal levels. Results The concentration of 12.5 mg/ kg showed the least therapeutic effect and 50 mg/ kg had the highest therapeutic effect for osteoporosis. The results of blood parameters involved in inflammation in both healthy and patient groups showed that the use of complete adjuvant induction causes joint inflammation. In the study of the interaction of the concentrations, it was observed that the concentration of 50 mg/ kg had the highest therapeutic effect against the disease in the studied mice. Conclusion The results showed that the new healthy and viable supplement restores the blood osteoporotic and rheumatoid factors of the mice to normal.
title Effect of a new type of healthy and live food supplement on osteoporosis blood parameters and induced rheumatoid arthritis in Wistar rats
topic Tissues and Organs
url https://arxiv.org/abs/2501.19343