Carefree multiple testing with e-processes

Fuente: arXiv
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Autores principales: Tavyrikov, Yury, Goeman, Jelle J., de Heide, Rianne
Formato: Preprint
Publicado: 2025
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author Tavyrikov, Yury
Goeman, Jelle J.
de Heide, Rianne
author_facet Tavyrikov, Yury
Goeman, Jelle J.
de Heide, Rianne
contents E-processes enable hypothesis testing with ongoing data collection while maintaining Type I error control. However, when testing multiple hypotheses simultaneously, current $e$-value based multiple testing methods such as e-BH are not invariant to the order in which data are gathered for the different $e$-processes. This can lead to undesirable situations, e.g., where a hypothesis rejected at time $t$ is no longer rejected at time $t+1$ after choosing to gather more data for one or more $e$-processes unrelated to that hypothesis. We argue that multiple testing methods should always work with suprema of $e$-processes. We provide an example to illustrate that e-BH does not control the FDR, at level $α$ when applied to suprema of $e$-processes. From the same example we see that the FWER is not controlled with averaging, and also closed e-BH does not control the FDR. We show that adjusters can be used to ensure FDR-sup control with e-BH under arbitrary dependence.
format Preprint
id arxiv_https___arxiv_org_abs_2501_19360
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Carefree multiple testing with e-processes
Tavyrikov, Yury
Goeman, Jelle J.
de Heide, Rianne
Statistics Theory
Methodology
E-processes enable hypothesis testing with ongoing data collection while maintaining Type I error control. However, when testing multiple hypotheses simultaneously, current $e$-value based multiple testing methods such as e-BH are not invariant to the order in which data are gathered for the different $e$-processes. This can lead to undesirable situations, e.g., where a hypothesis rejected at time $t$ is no longer rejected at time $t+1$ after choosing to gather more data for one or more $e$-processes unrelated to that hypothesis. We argue that multiple testing methods should always work with suprema of $e$-processes. We provide an example to illustrate that e-BH does not control the FDR, at level $α$ when applied to suprema of $e$-processes. From the same example we see that the FWER is not controlled with averaging, and also closed e-BH does not control the FDR. We show that adjusters can be used to ensure FDR-sup control with e-BH under arbitrary dependence.
title Carefree multiple testing with e-processes
topic Statistics Theory
Methodology
url https://arxiv.org/abs/2501.19360