Evaluating Deep Human-in-the-Loop Optimization for Retinal Implants Using Sighted Participants

Fuente: arXiv
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Auteurs principaux: Schoinas, Eirini, Rastogi, Adyah, Carter, Anissa, Granley, Jacob, Beyeler, Michael
Format: Preprint
Publié: 2025
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author Schoinas, Eirini
Rastogi, Adyah
Carter, Anissa
Granley, Jacob
Beyeler, Michael
author_facet Schoinas, Eirini
Rastogi, Adyah
Carter, Anissa
Granley, Jacob
Beyeler, Michael
contents Human-in-the-loop optimization (HILO) is a promising approach for personalizing visual prostheses by iteratively refining stimulus parameters based on user feedback. Previous work demonstrated HILO's efficacy in simulation, but its performance with human participants remains untested. Here we evaluate HILO using sighted participants viewing simulated prosthetic vision to assess its ability to optimize stimulation strategies under realistic conditions. Participants selected between phosphenes generated by competing encoders to iteratively refine a deep stimulus encoder (DSE). We tested HILO in three conditions: standard optimization, threshold misspecifications, and out-of-distribution parameter sampling. Participants consistently preferred HILO-generated stimuli over both a naive encoder and the DSE alone, with log odds favoring HILO across all conditions. We also observed key differences between human and simulated decision-making, highlighting the importance of validating optimization strategies with human participants. These findings support HILO as a viable approach for adapting visual prostheses to individuals. Clinical relevance: Validating HILO with sighted participants viewing simulated prosthetic vision is an important step toward personalized calibration of future visual prostheses.
format Preprint
id arxiv_https___arxiv_org_abs_2502_00177
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Evaluating Deep Human-in-the-Loop Optimization for Retinal Implants Using Sighted Participants
Schoinas, Eirini
Rastogi, Adyah
Carter, Anissa
Granley, Jacob
Beyeler, Michael
Machine Learning
Computer Vision and Pattern Recognition
Human-Computer Interaction
I.2.10
Human-in-the-loop optimization (HILO) is a promising approach for personalizing visual prostheses by iteratively refining stimulus parameters based on user feedback. Previous work demonstrated HILO's efficacy in simulation, but its performance with human participants remains untested. Here we evaluate HILO using sighted participants viewing simulated prosthetic vision to assess its ability to optimize stimulation strategies under realistic conditions. Participants selected between phosphenes generated by competing encoders to iteratively refine a deep stimulus encoder (DSE). We tested HILO in three conditions: standard optimization, threshold misspecifications, and out-of-distribution parameter sampling. Participants consistently preferred HILO-generated stimuli over both a naive encoder and the DSE alone, with log odds favoring HILO across all conditions. We also observed key differences between human and simulated decision-making, highlighting the importance of validating optimization strategies with human participants. These findings support HILO as a viable approach for adapting visual prostheses to individuals. Clinical relevance: Validating HILO with sighted participants viewing simulated prosthetic vision is an important step toward personalized calibration of future visual prostheses.
title Evaluating Deep Human-in-the-Loop Optimization for Retinal Implants Using Sighted Participants
topic Machine Learning
Computer Vision and Pattern Recognition
Human-Computer Interaction
I.2.10
url https://arxiv.org/abs/2502.00177