Self-Prompt SAM: Medical Image Segmentation via Automatic Prompt SAM Adaptation

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Hauptverfasser: Xie, Bin, Tang, Hao, Cai, Dawen, Yan, Yan, Agam, Gady
Format: Preprint
Veröffentlicht: 2025
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author Xie, Bin
Tang, Hao
Cai, Dawen
Yan, Yan
Agam, Gady
author_facet Xie, Bin
Tang, Hao
Cai, Dawen
Yan, Yan
Agam, Gady
contents Segment Anything Model (SAM) has demonstrated impressive zero-shot performance and brought a range of unexplored capabilities to natural image segmentation tasks. However, as a very important branch of image segmentation, the performance of SAM remains uncertain when applied to medical image segmentation due to the significant differences between natural images and medical images. Meanwhile, it is harsh to meet the SAM's requirements of extra prompts provided, such as points or boxes to specify medical regions. In this paper, we propose a novel self-prompt SAM adaptation framework for medical image segmentation, named Self-Prompt-SAM. We design a multi-scale prompt generator combined with the image encoder in SAM to generate auxiliary masks. Then, we use the auxiliary masks to generate bounding boxes as box prompts and use Distance Transform to select the most central points as point prompts. Meanwhile, we design a 3D depth-fused adapter (DfusedAdapter) and inject the DFusedAdapter into each transformer in the image encoder and mask decoder to enable pre-trained 2D SAM models to extract 3D information and adapt to 3D medical images. Extensive experiments demonstrate that our method achieves state-of-the-art performance and outperforms nnUNet by 2.3% on AMOS2022, 1.6% on ACDCand 0.5% on Synapse datasets.
format Preprint
id arxiv_https___arxiv_org_abs_2502_00630
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Self-Prompt SAM: Medical Image Segmentation via Automatic Prompt SAM Adaptation
Xie, Bin
Tang, Hao
Cai, Dawen
Yan, Yan
Agam, Gady
Computer Vision and Pattern Recognition
Segment Anything Model (SAM) has demonstrated impressive zero-shot performance and brought a range of unexplored capabilities to natural image segmentation tasks. However, as a very important branch of image segmentation, the performance of SAM remains uncertain when applied to medical image segmentation due to the significant differences between natural images and medical images. Meanwhile, it is harsh to meet the SAM's requirements of extra prompts provided, such as points or boxes to specify medical regions. In this paper, we propose a novel self-prompt SAM adaptation framework for medical image segmentation, named Self-Prompt-SAM. We design a multi-scale prompt generator combined with the image encoder in SAM to generate auxiliary masks. Then, we use the auxiliary masks to generate bounding boxes as box prompts and use Distance Transform to select the most central points as point prompts. Meanwhile, we design a 3D depth-fused adapter (DfusedAdapter) and inject the DFusedAdapter into each transformer in the image encoder and mask decoder to enable pre-trained 2D SAM models to extract 3D information and adapt to 3D medical images. Extensive experiments demonstrate that our method achieves state-of-the-art performance and outperforms nnUNet by 2.3% on AMOS2022, 1.6% on ACDCand 0.5% on Synapse datasets.
title Self-Prompt SAM: Medical Image Segmentation via Automatic Prompt SAM Adaptation
topic Computer Vision and Pattern Recognition
url https://arxiv.org/abs/2502.00630