Many-Body Coarse-Grained Molecular Dynamics with the Atomic Cluster Expansion

Fuente: arXiv
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Main Authors: Wang, Yangshuai, Csanyi, Gabor, Ortner, Christoph
Format: Preprint
Published: 2025
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author Wang, Yangshuai
Csanyi, Gabor
Ortner, Christoph
author_facet Wang, Yangshuai
Csanyi, Gabor
Ortner, Christoph
contents Molecular dynamics (MD) simulations provide detailed insight into atomic-scale mechanisms but are inherently restricted to small spatio-temporal scales. Coarse-grained molecular dynamics (CGMD) techniques allow simulations of much larger systems over extended timescales. In theory, these techniques can be quantitatively accurate, but common practice is to only target qualitatively correct behaviour of coarse-grained models. Recent advances in applying machine learning methodology in this setting are now being applied to create also quantitatively accurate CGMD models. We demonstrate how the Atomic Cluster Expansion parameterization (Drautz, 2019) can be used in this task to construct highly efficient, interpretable and accurate CGMD models. We focus in particular on exploring the role of many-body effects.
format Preprint
id arxiv_https___arxiv_org_abs_2502_04661
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Many-Body Coarse-Grained Molecular Dynamics with the Atomic Cluster Expansion
Wang, Yangshuai
Csanyi, Gabor
Ortner, Christoph
Computational Physics
Molecular dynamics (MD) simulations provide detailed insight into atomic-scale mechanisms but are inherently restricted to small spatio-temporal scales. Coarse-grained molecular dynamics (CGMD) techniques allow simulations of much larger systems over extended timescales. In theory, these techniques can be quantitatively accurate, but common practice is to only target qualitatively correct behaviour of coarse-grained models. Recent advances in applying machine learning methodology in this setting are now being applied to create also quantitatively accurate CGMD models. We demonstrate how the Atomic Cluster Expansion parameterization (Drautz, 2019) can be used in this task to construct highly efficient, interpretable and accurate CGMD models. We focus in particular on exploring the role of many-body effects.
title Many-Body Coarse-Grained Molecular Dynamics with the Atomic Cluster Expansion
topic Computational Physics
url https://arxiv.org/abs/2502.04661