ARTInp: CBCT-to-CT Image Inpainting and Image Translation in Radiotherapy

Fuente: arXiv
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Autores principales: Brioso, Ricardo Coimbra, Crespi, Leonardo, Seghetto, Andrea, Dei, Damiano, Lambri, Nicola, Mancosu, Pietro, Scorsetti, Marta, Loiacono, Daniele
Formato: Preprint
Publicado: 2025
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author Brioso, Ricardo Coimbra
Crespi, Leonardo
Seghetto, Andrea
Dei, Damiano
Lambri, Nicola
Mancosu, Pietro
Scorsetti, Marta
Loiacono, Daniele
author_facet Brioso, Ricardo Coimbra
Crespi, Leonardo
Seghetto, Andrea
Dei, Damiano
Lambri, Nicola
Mancosu, Pietro
Scorsetti, Marta
Loiacono, Daniele
contents A key step in Adaptive Radiation Therapy (ART) workflows is the evaluation of the patient's anatomy at treatment time to ensure the accuracy of the delivery. To this end, Cone Beam Computerized Tomography (CBCT) is widely used being cost-effective and easy to integrate into the treatment process. Nonetheless, CBCT images have lower resolution and more artifacts than CT scans, making them less reliable for precise treatment validation. Moreover, in complex treatments such as Total Marrow and Lymph Node Irradiation (TMLI), where full-body visualization of the patient is critical for accurate dose delivery, the CBCT images are often discontinuous, leaving gaps that could contain relevant anatomical information. To address these limitations, we propose ARTInp (Adaptive Radiation Therapy Inpainting), a novel deep-learning framework combining image inpainting and CBCT-to-CT translation. ARTInp employs a dual-network approach: a completion network that fills anatomical gaps in CBCT volumes and a custom Generative Adversarial Network (GAN) to generate high-quality synthetic CT (sCT) images. We trained ARTInp on a dataset of paired CBCT and CT images from the SynthRad 2023 challenge, and the performance achieved on a test set of 18 patients demonstrates its potential for enhancing CBCT-based workflows in radiotherapy.
format Preprint
id arxiv_https___arxiv_org_abs_2502_04898
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle ARTInp: CBCT-to-CT Image Inpainting and Image Translation in Radiotherapy
Brioso, Ricardo Coimbra
Crespi, Leonardo
Seghetto, Andrea
Dei, Damiano
Lambri, Nicola
Mancosu, Pietro
Scorsetti, Marta
Loiacono, Daniele
Image and Video Processing
Artificial Intelligence
Computer Vision and Pattern Recognition
A key step in Adaptive Radiation Therapy (ART) workflows is the evaluation of the patient's anatomy at treatment time to ensure the accuracy of the delivery. To this end, Cone Beam Computerized Tomography (CBCT) is widely used being cost-effective and easy to integrate into the treatment process. Nonetheless, CBCT images have lower resolution and more artifacts than CT scans, making them less reliable for precise treatment validation. Moreover, in complex treatments such as Total Marrow and Lymph Node Irradiation (TMLI), where full-body visualization of the patient is critical for accurate dose delivery, the CBCT images are often discontinuous, leaving gaps that could contain relevant anatomical information. To address these limitations, we propose ARTInp (Adaptive Radiation Therapy Inpainting), a novel deep-learning framework combining image inpainting and CBCT-to-CT translation. ARTInp employs a dual-network approach: a completion network that fills anatomical gaps in CBCT volumes and a custom Generative Adversarial Network (GAN) to generate high-quality synthetic CT (sCT) images. We trained ARTInp on a dataset of paired CBCT and CT images from the SynthRad 2023 challenge, and the performance achieved on a test set of 18 patients demonstrates its potential for enhancing CBCT-based workflows in radiotherapy.
title ARTInp: CBCT-to-CT Image Inpainting and Image Translation in Radiotherapy
topic Image and Video Processing
Artificial Intelligence
Computer Vision and Pattern Recognition
url https://arxiv.org/abs/2502.04898