Cover Image

Joint TITE-CRM for Dual Agent Dose Finding Studies

Fuente: arXiv

Saved in:

Bibliographic Details
Main Authors:	Barnett, Helen, Boix, Oliver, Kontos, Dimitris, Jaki, Thomas
Format:	Preprint
Published:	2025
Subjects:	Applications
Online Access:	Acceder al recurso
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

TITE-CLRM: Towards efficient time-to-event dose-escalation guidance of multi-cycle cancer therapies
by: Widmer, Lukas Andreas, et al.
Published: (2024)

A multi-arm multi-stage design for trials with all pairwise testing
by: Greenstreet, Peter, et al.
Published: (2025)

Evaluating Predictive Modeling Strategies for Predicting Individual Treatment Effects in Precision Medicine
by: Chiroque-Solano, Pamela M., et al.
Published: (2026)

The Backfill i3+3 Design for Dose-Finding Trials in Oncology
by: Liu, Jiaxin, et al.
Published: (2023)

Pharmacokinetic Measurements in Dose Finding Model Guided by Escalation with Overdose Control
by: Maity, Arnab Kumar, et al.
Published: (2024)

Goodness-of-Fit Checks for Joint Models
by: Rizopoulos, Dimitris, et al.
Published: (2026)

Straightforward Phase I Dose-Finding Design for Healthy Volunteers Accounting for Surrogate Activity Biomarkers
by: Boulet, Sandrine, et al.
Published: (2024)

The Modified Combo i3+3 Design for Novel-Novel Combination Dose-Finding Trials in Oncology
by: Liu, Jiaxin, et al.
Published: (2024)

Precision Dose-Finding Design for Phase I Oncology Trials by Integrating Pharmacology Data
by: Lee, Kyong Ju, et al.
Published: (2025)

A Bayesian Additive Regression Trees Model for zero and one inflated data for Predicting Individual Treatment Effects in Alcohol Use Disorder Trials
by: Solano, Pamela, et al.
Published: (2025)

Defining Utility as a Measure of Preference Under Uncertainty in Phase I-II Oncology Dose Finding Trials
by: Hall, Andrew, et al.
Published: (2025)

A Bayesian Joint Modelling for Misclassified Interval-censoring and Competing Risks
by: Yang, Zhenwei, et al.
Published: (2024)

Personalized Biopsy Schedules Using an Interval-censored Cause-specific Joint Model
by: Yang, Zhenwei, et al.
Published: (2022)

Exploring Monetary Policy Shocks with Large-Scale Bayesian VARs
by: Korobilis, Dimitris
Published: (2025)

Confidence intervals for adaptive trial designs II: Case study and practical guidance
by: Robertson, David S., et al.
Published: (2024)

Confidence intervals for adaptive trial designs I: A methodological review
by: Robertson, David S., et al.
Published: (2024)

Adaptive Weighting for Time-to-Event Continual Reassessment Method: Improving Safety in Phase I Dose-Finding Through Data-Driven Delay Distribution Estimation
by: Amevor, Robert, et al.
Published: (2026)

BOIN Designs for Dose Escalation With Selected Dose Combinations in Oncology Phase I Trials
by: Chen, Yuxuan, et al.
Published: (2026)

Adaptive Phase 2/3 Design with Dose Optimization
by: Chen, Cong, et al.
Published: (2024)

Learning from crises: A new class of time-varying parameter VARs with observable adaptation
by: Hardy, Nicolas, et al.
Published: (2025)

Subdata selection for big data regression: an improved approach
by: Chasiotis, Vasilis, et al.
Published: (2023)

Near-real-time ship grounding damage assessment using Bayesian networks
by: Georgiadis, Dimitris G., et al.
Published: (2025)

Adjustment for Inconsistency in Adaptive Phase 2/3 Designs with Dose Optimization
by: Chen, Cong, et al.
Published: (2025)

Network Meta Analysis of Mean Survival
by: Apsemidis, Anastasios, et al.
Published: (2025)

A Utility Score Framework for Dose Optimization Studies with Binary Efficacy-Safety Endpoints: Sample Size Determination and Bias Characterization
by: Gu, Xuemin, et al.
Published: (2026)

Contrastive CUR: Interpretable Joint Feature and Sample Selection for Case-Control Studies
by: Zhang, Eric, et al.
Published: (2025)

Prioritizing Variables for Observational Study Design using the Joint Variable Importance Plot
by: Liao, Lauren D., et al.
Published: (2023)

Joint Object Tracking and Intent Recognition
by: Liang, Jiaming, et al.
Published: (2023)

Feasible Dose-Response Curves for Continuous Treatments Under Positivity Violations
by: Bao, Han, et al.
Published: (2025)

Power Estimation for Longitudinal Studies with Time Dependent Covariates Using Generalized Method of Moments
by: Ramezani, Niloofar, et al.
Published: (2026)

Game Theory and Dual Approach to the Dynamic Programming on the Example of the COVID‐19 Pandemic in Poland Described by Mathematical Model With Three‐Dose Vaccinated
by: Radosław Matusik
Published: (2024)

Impacts of Dams on Fish Species Assemblage and Functional Trait Composition Within Two Alabama Drainages
by: Zanethia C. Barnett, et al.
Published: (2025)

Dose optimization design accounting for unknown patient heterogeneity in cancer clinical trials
by: Silva, Rebecca B., et al.
Published: (2025)

Jointly Estimating Subnational Mortality for Multiple Populations
by: Dharamshi, Ameer, et al.
Published: (2023)

Agent modelling, statistical control, and the strength of middle knowledge
by: Chesney, Thomas, et al.
Published: (2024)

Evaluating Bias Reduction Methods in Binary Emax Model for Reliable Dose-Response Estimation
by: Zhang, Jiangshan, et al.
Published: (2025)

HAL-Based Plug-in Estimation with Pointwise Asymptotic Normality of the Causal Dose-Response Curve
by: Shi, Junming, et al.
Published: (2024)

A Seamless Phase II/III Design with Dose Optimization for Oncology Drug Development
by: Li, Yuhan, et al.
Published: (2024)

DEMO: Dose Exploration, Monitoring, and Optimization Using a Biological Mediator for Clinical Outcomes
by: Yang, Cheng-Han, et al.
Published: (2024)

Flexible Models for Simple Longitudinal Data
by: Ogden, Helen
Published: (2024)