Pulling back the curtain: the road from statistical estimand to machine-learning based estimator for epidemiologists (no wizard required)

Fuente: arXiv
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Hauptverfasser: Renson, Audrey, Montoya, Lina, Goin, Dana E., Díaz, Iván, Ross, Rachael K.
Format: Preprint
Veröffentlicht: 2025
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author Renson, Audrey
Montoya, Lina
Goin, Dana E.
Díaz, Iván
Ross, Rachael K.
author_facet Renson, Audrey
Montoya, Lina
Goin, Dana E.
Díaz, Iván
Ross, Rachael K.
contents Epidemiologists increasingly use causal inference methods that rely on machine learning, as these approaches can relax unnecessary model specification assumptions. While deriving and studying asymptotic properties of such estimators is a task usually associated with statisticians, it is useful for epidemiologists to understand the steps involved, as epidemiologists are often at the forefront of defining important new research questions and translating them into new parameters to be estimated. In this paper, our goal was to provide a relatively accessible guide through the process of (i) deriving an estimator based on the so-called efficient influence function (which we define and explain), and (ii) showing such an estimator's ability to validly incorporate machine learning, by demonstrating the so-called rate double robustness property. The derivations in this paper rely mainly on algebra and some foundational results from statistical inference, which are explained.
format Preprint
id arxiv_https___arxiv_org_abs_2502_05363
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Pulling back the curtain: the road from statistical estimand to machine-learning based estimator for epidemiologists (no wizard required)
Renson, Audrey
Montoya, Lina
Goin, Dana E.
Díaz, Iván
Ross, Rachael K.
Methodology
Applications
Epidemiologists increasingly use causal inference methods that rely on machine learning, as these approaches can relax unnecessary model specification assumptions. While deriving and studying asymptotic properties of such estimators is a task usually associated with statisticians, it is useful for epidemiologists to understand the steps involved, as epidemiologists are often at the forefront of defining important new research questions and translating them into new parameters to be estimated. In this paper, our goal was to provide a relatively accessible guide through the process of (i) deriving an estimator based on the so-called efficient influence function (which we define and explain), and (ii) showing such an estimator's ability to validly incorporate machine learning, by demonstrating the so-called rate double robustness property. The derivations in this paper rely mainly on algebra and some foundational results from statistical inference, which are explained.
title Pulling back the curtain: the road from statistical estimand to machine-learning based estimator for epidemiologists (no wizard required)
topic Methodology
Applications
url https://arxiv.org/abs/2502.05363