Approximate Bayesian inference for joint partially linear modeling of longitudinal measurements and spatial time-to-event data

Fuente: arXiv
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Autori principali: Baghfalaki, Taban, Ganjali, Mojtaba, Martins, Rui
Natura: Preprint
Pubblicazione: 2025
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author Baghfalaki, Taban
Ganjali, Mojtaba
Martins, Rui
author_facet Baghfalaki, Taban
Ganjali, Mojtaba
Martins, Rui
contents The integration of longitudinal measurements and survival time in statistical modeling offers a powerful framework for capturing the interplay between these two essential outcomes, particularly when they exhibit associations. However, in scenarios where spatial dependencies among entities are present due to geographic regions, traditional approaches may fall short. In response, this paper introduces a novel approximate Bayesian hierarchical model tailored for jointly analyzing longitudinal and spatial survival outcomes. The model leverages a conditional autoregressive structure to incorporate spatial effects, while simultaneously employing a joint partially linear model to capture the nonlinear influence of time on longitudinal responses. Through extensive simulation studies, the efficacy of the proposed method is rigorously evaluated. Furthermore, its practical utility is demonstrated through an application to real-world HIV/AIDS data sourced from various Brazilian states, showcasing its adaptability and relevance in epidemiological research.
format Preprint
id arxiv_https___arxiv_org_abs_2502_05880
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Approximate Bayesian inference for joint partially linear modeling of longitudinal measurements and spatial time-to-event data
Baghfalaki, Taban
Ganjali, Mojtaba
Martins, Rui
Methodology
Computation
The integration of longitudinal measurements and survival time in statistical modeling offers a powerful framework for capturing the interplay between these two essential outcomes, particularly when they exhibit associations. However, in scenarios where spatial dependencies among entities are present due to geographic regions, traditional approaches may fall short. In response, this paper introduces a novel approximate Bayesian hierarchical model tailored for jointly analyzing longitudinal and spatial survival outcomes. The model leverages a conditional autoregressive structure to incorporate spatial effects, while simultaneously employing a joint partially linear model to capture the nonlinear influence of time on longitudinal responses. Through extensive simulation studies, the efficacy of the proposed method is rigorously evaluated. Furthermore, its practical utility is demonstrated through an application to real-world HIV/AIDS data sourced from various Brazilian states, showcasing its adaptability and relevance in epidemiological research.
title Approximate Bayesian inference for joint partially linear modeling of longitudinal measurements and spatial time-to-event data
topic Methodology
Computation
url https://arxiv.org/abs/2502.05880