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Main Authors: Evans, Nicholas, Baker, Stephen, Reed, Miles
Format: Preprint
Published: 2025
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Online Access:https://arxiv.org/abs/2502.05926
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author Evans, Nicholas
Baker, Stephen
Reed, Miles
author_facet Evans, Nicholas
Baker, Stephen
Reed, Miles
contents The rapid advancements in large language models (LLMs) have unlocked their potential for multimodal tasks, where text and visual data are processed jointly. However, applying LLMs to medical imaging, particularly for chest X-rays (CXR), poses significant challenges due to the need for precise visual-textual alignment and the preservation of critical diagnostic details. In this paper, we propose Multi-Stage Adaptive Vision-Language Tuning (MAViLT), a novel framework designed to enhance multimodal reasoning and generation for CXR understanding. MAViLT incorporates a clinical gradient-weighted tokenization process and a hierarchical fine-tuning strategy, enabling it to generate accurate radiology reports, synthesize realistic CXRs from text, and answer vision-based clinical questions. We evaluate MAViLT on two benchmark datasets, MIMIC-CXR and Indiana University CXR, achieving state-of-the-art results across all tasks. Human evaluations further validate the clinical relevance and utility of MAViLT, making it a robust tool for real-world medical applications. This work demonstrates the feasibility of leveraging LLMs for multimodal medical imaging while addressing key challenges in vision-language integration.
format Preprint
id arxiv_https___arxiv_org_abs_2502_05926
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle A Generative Framework for Bidirectional Image-Report Understanding in Chest Radiography
Evans, Nicholas
Baker, Stephen
Reed, Miles
Image and Video Processing
Computation and Language
Computer Vision and Pattern Recognition
The rapid advancements in large language models (LLMs) have unlocked their potential for multimodal tasks, where text and visual data are processed jointly. However, applying LLMs to medical imaging, particularly for chest X-rays (CXR), poses significant challenges due to the need for precise visual-textual alignment and the preservation of critical diagnostic details. In this paper, we propose Multi-Stage Adaptive Vision-Language Tuning (MAViLT), a novel framework designed to enhance multimodal reasoning and generation for CXR understanding. MAViLT incorporates a clinical gradient-weighted tokenization process and a hierarchical fine-tuning strategy, enabling it to generate accurate radiology reports, synthesize realistic CXRs from text, and answer vision-based clinical questions. We evaluate MAViLT on two benchmark datasets, MIMIC-CXR and Indiana University CXR, achieving state-of-the-art results across all tasks. Human evaluations further validate the clinical relevance and utility of MAViLT, making it a robust tool for real-world medical applications. This work demonstrates the feasibility of leveraging LLMs for multimodal medical imaging while addressing key challenges in vision-language integration.
title A Generative Framework for Bidirectional Image-Report Understanding in Chest Radiography
topic Image and Video Processing
Computation and Language
Computer Vision and Pattern Recognition
url https://arxiv.org/abs/2502.05926