On the Reliability of Information Retrieval From MDS Coded Data in DNA Storage

Fuente: arXiv
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Main Author: Hanna, Serge Kas
Format: Preprint
Published: 2025
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author Hanna, Serge Kas
author_facet Hanna, Serge Kas
contents This work presents a theoretical analysis of the probability of successfully retrieving data encoded with MDS codes (e.g., Reed-Solomon codes) in DNA storage systems. We study this probability under independent and identically distributed (i.i.d.) substitution errors, focusing on a common code design strategy that combines inner and outer MDS codes. Our analysis demonstrates how this probability depends on factors such as the total number of sequencing reads, their distribution across strands, the rates of the inner and outer codes, and the substitution error probabilities. These results provide actionable insights into optimizing DNA storage systems under reliability constraints, including determining the minimum number of sequencing reads needed for reliable data retrieval and identifying the optimal balance between the rates of inner and outer MDS codes.
format Preprint
id arxiv_https___arxiv_org_abs_2502_06618
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle On the Reliability of Information Retrieval From MDS Coded Data in DNA Storage
Hanna, Serge Kas
Information Theory
Emerging Technologies
This work presents a theoretical analysis of the probability of successfully retrieving data encoded with MDS codes (e.g., Reed-Solomon codes) in DNA storage systems. We study this probability under independent and identically distributed (i.i.d.) substitution errors, focusing on a common code design strategy that combines inner and outer MDS codes. Our analysis demonstrates how this probability depends on factors such as the total number of sequencing reads, their distribution across strands, the rates of the inner and outer codes, and the substitution error probabilities. These results provide actionable insights into optimizing DNA storage systems under reliability constraints, including determining the minimum number of sequencing reads needed for reliable data retrieval and identifying the optimal balance between the rates of inner and outer MDS codes.
title On the Reliability of Information Retrieval From MDS Coded Data in DNA Storage
topic Information Theory
Emerging Technologies
url https://arxiv.org/abs/2502.06618