Individualised Treatment Effects Estimation with Composite Treatments and Composite Outcomes

Fuente: arXiv
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Auteurs principaux: Chauhan, Vinod Kumar, Clifton, Lei, Nigam, Gaurav, Clifton, David A.
Format: Preprint
Publié: 2025
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author Chauhan, Vinod Kumar
Clifton, Lei
Nigam, Gaurav
Clifton, David A.
author_facet Chauhan, Vinod Kumar
Clifton, Lei
Nigam, Gaurav
Clifton, David A.
contents Estimating individualised treatment effect (ITE) -- that is the causal effect of a set of variables (also called exposures, treatments, actions, policies, or interventions), referred to as \textit{composite treatments}, on a set of outcome variables of interest, referred to as \textit{composite outcomes}, for a unit from observational data -- remains a fundamental problem in causal inference with applications across disciplines, such as healthcare, economics, education, social science, marketing, and computer science. Previous work in causal machine learning for ITE estimation is limited to simple settings, like single treatments and single outcomes. This hinders their use in complex real-world scenarios; for example, consider studying the effect of different ICU interventions, such as beta-blockers and statins for a patient admitted for heart surgery, on different outcomes of interest such as atrial fibrillation and in-hospital mortality. The limited research into composite treatments and outcomes is primarily due to data scarcity for all treatments and outcomes. To address the above challenges, we propose a novel and innovative hypernetwork-based approach, called \emph{H-Learner}, to solve ITE estimation under composite treatments and composite outcomes, which tackles the data scarcity issue by dynamically sharing information across treatments and outcomes. Our empirical analysis with binary and arbitrary composite treatments and outcomes demonstrates the effectiveness of the proposed approach compared to existing methods.
format Preprint
id arxiv_https___arxiv_org_abs_2502_08282
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Individualised Treatment Effects Estimation with Composite Treatments and Composite Outcomes
Chauhan, Vinod Kumar
Clifton, Lei
Nigam, Gaurav
Clifton, David A.
Machine Learning
Artificial Intelligence
Estimating individualised treatment effect (ITE) -- that is the causal effect of a set of variables (also called exposures, treatments, actions, policies, or interventions), referred to as \textit{composite treatments}, on a set of outcome variables of interest, referred to as \textit{composite outcomes}, for a unit from observational data -- remains a fundamental problem in causal inference with applications across disciplines, such as healthcare, economics, education, social science, marketing, and computer science. Previous work in causal machine learning for ITE estimation is limited to simple settings, like single treatments and single outcomes. This hinders their use in complex real-world scenarios; for example, consider studying the effect of different ICU interventions, such as beta-blockers and statins for a patient admitted for heart surgery, on different outcomes of interest such as atrial fibrillation and in-hospital mortality. The limited research into composite treatments and outcomes is primarily due to data scarcity for all treatments and outcomes. To address the above challenges, we propose a novel and innovative hypernetwork-based approach, called \emph{H-Learner}, to solve ITE estimation under composite treatments and composite outcomes, which tackles the data scarcity issue by dynamically sharing information across treatments and outcomes. Our empirical analysis with binary and arbitrary composite treatments and outcomes demonstrates the effectiveness of the proposed approach compared to existing methods.
title Individualised Treatment Effects Estimation with Composite Treatments and Composite Outcomes
topic Machine Learning
Artificial Intelligence
url https://arxiv.org/abs/2502.08282