Mathematical modeling and simulation of coupled aqueous humor flow and temperature distribution in a realistic 3D human eye geometry

Fuente: arXiv
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Autori principali: Saigre, Thomas, Chabannes, Vincent, Prud'Homme, Christophe, Szopos, Marcela
Natura: Preprint
Pubblicazione: 2025
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author Saigre, Thomas
Chabannes, Vincent
Prud'Homme, Christophe
Szopos, Marcela
author_facet Saigre, Thomas
Chabannes, Vincent
Prud'Homme, Christophe
Szopos, Marcela
contents We present a comprehensive computational model to simulate the coupled dynamics of aqueous humor flow and heat transfer in the human eye. To manage the complexity of the model, we make significant efforts in meshing and efficient solution of the discrete problem using high-performance resources. The model accurately describes the dynamics of the aqueous humor in the anterior and posterior chambers and accounts for convective effects due to temperature variations. Results for fluid velocity, pressure, and temperature distribution are in good agreement with existing numerical results in the literature. Furthermore, the effects of postural changes and wall shear stress behavior are analyzed, providing new insights into the mechanical forces acting on ocular tissues. Overall, the present contribution provides a detailed three-dimensional simulation that enhances the understanding of ocular physiology and may contribute to further progress in clinical research and treatment optimization in ophthalmology.
format Preprint
id arxiv_https___arxiv_org_abs_2502_09119
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Mathematical modeling and simulation of coupled aqueous humor flow and temperature distribution in a realistic 3D human eye geometry
Saigre, Thomas
Chabannes, Vincent
Prud'Homme, Christophe
Szopos, Marcela
Analysis of PDEs
We present a comprehensive computational model to simulate the coupled dynamics of aqueous humor flow and heat transfer in the human eye. To manage the complexity of the model, we make significant efforts in meshing and efficient solution of the discrete problem using high-performance resources. The model accurately describes the dynamics of the aqueous humor in the anterior and posterior chambers and accounts for convective effects due to temperature variations. Results for fluid velocity, pressure, and temperature distribution are in good agreement with existing numerical results in the literature. Furthermore, the effects of postural changes and wall shear stress behavior are analyzed, providing new insights into the mechanical forces acting on ocular tissues. Overall, the present contribution provides a detailed three-dimensional simulation that enhances the understanding of ocular physiology and may contribute to further progress in clinical research and treatment optimization in ophthalmology.
title Mathematical modeling and simulation of coupled aqueous humor flow and temperature distribution in a realistic 3D human eye geometry
topic Analysis of PDEs
url https://arxiv.org/abs/2502.09119