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Main Authors: Sheng, Jiabao, Lam, SaiKit, Zhang, Jiang, Zhang, Yuanpeng, Cai, Jing
Format: Preprint
Published: 2025
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Online Access:https://arxiv.org/abs/2502.09656
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author Sheng, Jiabao
Lam, SaiKit
Zhang, Jiang
Zhang, Yuanpeng
Cai, Jing
author_facet Sheng, Jiabao
Lam, SaiKit
Zhang, Jiang
Zhang, Yuanpeng
Cai, Jing
contents Omics fusion has emerged as a crucial preprocessing approach in the field of medical image processing, providing significant assistance to several studies. One of the challenges encountered in the integration of omics data is the presence of unpredictability arising from disparities in data sources and medical imaging equipment. In order to overcome this challenge and facilitate the integration of their joint application to specific medical objectives, this study aims to develop a fusion methodology that mitigates the disparities inherent in omics data. The utilization of the multi-kernel late-fusion method has gained significant popularity as an effective strategy for addressing this particular challenge. An efficient representation of the data may be achieved by utilizing a suitable single-kernel function to map the inherent features and afterward merging them in a space with a high number of dimensions. This approach effectively addresses the differences noted before. The inflexibility of label fitting poses a constraint on the use of multi-kernel late-fusion methods in complex nasopharyngeal carcinoma (NPC) datasets, hence affecting the efficacy of general classifiers in dealing with high-dimensional characteristics. This innovative methodology aims to increase the disparity between the two cohorts, hence providing a more flexible structure for the allocation of labels. The examination of the NPC-ContraParotid dataset demonstrates the model's robustness and efficacy, indicating its potential as a valuable tool for predicting distant metastases in patients with nasopharyngeal carcinoma (NPC).
format Preprint
id arxiv_https___arxiv_org_abs_2502_09656
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Multi-Omics Fusion with Soft Labeling for Enhanced Prediction of Distant Metastasis in Nasopharyngeal Carcinoma Patients after Radiotherapy
Sheng, Jiabao
Lam, SaiKit
Zhang, Jiang
Zhang, Yuanpeng
Cai, Jing
Quantitative Methods
Computer Vision and Pattern Recognition
Image and Video Processing
Omics fusion has emerged as a crucial preprocessing approach in the field of medical image processing, providing significant assistance to several studies. One of the challenges encountered in the integration of omics data is the presence of unpredictability arising from disparities in data sources and medical imaging equipment. In order to overcome this challenge and facilitate the integration of their joint application to specific medical objectives, this study aims to develop a fusion methodology that mitigates the disparities inherent in omics data. The utilization of the multi-kernel late-fusion method has gained significant popularity as an effective strategy for addressing this particular challenge. An efficient representation of the data may be achieved by utilizing a suitable single-kernel function to map the inherent features and afterward merging them in a space with a high number of dimensions. This approach effectively addresses the differences noted before. The inflexibility of label fitting poses a constraint on the use of multi-kernel late-fusion methods in complex nasopharyngeal carcinoma (NPC) datasets, hence affecting the efficacy of general classifiers in dealing with high-dimensional characteristics. This innovative methodology aims to increase the disparity between the two cohorts, hence providing a more flexible structure for the allocation of labels. The examination of the NPC-ContraParotid dataset demonstrates the model's robustness and efficacy, indicating its potential as a valuable tool for predicting distant metastases in patients with nasopharyngeal carcinoma (NPC).
title Multi-Omics Fusion with Soft Labeling for Enhanced Prediction of Distant Metastasis in Nasopharyngeal Carcinoma Patients after Radiotherapy
topic Quantitative Methods
Computer Vision and Pattern Recognition
Image and Video Processing
url https://arxiv.org/abs/2502.09656