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Hauptverfasser: Yang, Shuqi, Jing, Mingrui, Wang, Shuai, Kou, Jiaxin, Shi, Manfei, Xing, Weijie, Hu, Yan, Zhu, Zheng
Format: Preprint
Veröffentlicht: 2025
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Online-Zugang:https://arxiv.org/abs/2502.11861
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author Yang, Shuqi
Jing, Mingrui
Wang, Shuai
Kou, Jiaxin
Shi, Manfei
Xing, Weijie
Hu, Yan
Zhu, Zheng
author_facet Yang, Shuqi
Jing, Mingrui
Wang, Shuai
Kou, Jiaxin
Shi, Manfei
Xing, Weijie
Hu, Yan
Zhu, Zheng
contents This study reviewed the use of Large Language Models (LLMs) in healthcare, focusing on their training corpora, customization techniques, and evaluation metrics. A systematic search of studies from 2021 to 2024 identified 61 articles. Four types of corpora were used: clinical resources, literature, open-source datasets, and web-crawled data. Common construction techniques included pre-training, prompt engineering, and retrieval-augmented generation, with 44 studies combining multiple methods. Evaluation metrics were categorized into process, usability, and outcome metrics, with outcome metrics divided into model-based and expert-assessed outcomes. The study identified critical gaps in corpus fairness, which contributed to biases from geographic, cultural, and socio-economic factors. The reliance on unverified or unstructured data highlighted the need for better integration of evidence-based clinical guidelines. Future research should focus on developing a tiered corpus architecture with vetted sources and dynamic weighting, while ensuring model transparency. Additionally, the lack of standardized evaluation frameworks for domain-specific models called for comprehensive validation of LLMs in real-world healthcare settings.
format Preprint
id arxiv_https___arxiv_org_abs_2502_11861
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Exploring Large Language Models in Healthcare: Insights into Corpora Sources, Customization Strategies, and Evaluation Metrics
Yang, Shuqi
Jing, Mingrui
Wang, Shuai
Kou, Jiaxin
Shi, Manfei
Xing, Weijie
Hu, Yan
Zhu, Zheng
Computation and Language
This study reviewed the use of Large Language Models (LLMs) in healthcare, focusing on their training corpora, customization techniques, and evaluation metrics. A systematic search of studies from 2021 to 2024 identified 61 articles. Four types of corpora were used: clinical resources, literature, open-source datasets, and web-crawled data. Common construction techniques included pre-training, prompt engineering, and retrieval-augmented generation, with 44 studies combining multiple methods. Evaluation metrics were categorized into process, usability, and outcome metrics, with outcome metrics divided into model-based and expert-assessed outcomes. The study identified critical gaps in corpus fairness, which contributed to biases from geographic, cultural, and socio-economic factors. The reliance on unverified or unstructured data highlighted the need for better integration of evidence-based clinical guidelines. Future research should focus on developing a tiered corpus architecture with vetted sources and dynamic weighting, while ensuring model transparency. Additionally, the lack of standardized evaluation frameworks for domain-specific models called for comprehensive validation of LLMs in real-world healthcare settings.
title Exploring Large Language Models in Healthcare: Insights into Corpora Sources, Customization Strategies, and Evaluation Metrics
topic Computation and Language
url https://arxiv.org/abs/2502.11861