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Autores principales: Yan, Yang, Yue, Bingqing, Li, Qiaxuan, Huang, Man, Chen, Jingyu, Lan, Zhenzhong
Formato: Preprint
Publicado: 2025
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Acceso en línea:https://arxiv.org/abs/2502.13447
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author Yan, Yang
Yue, Bingqing
Li, Qiaxuan
Huang, Man
Chen, Jingyu
Lan, Zhenzhong
author_facet Yan, Yang
Yue, Bingqing
Li, Qiaxuan
Huang, Man
Chen, Jingyu
Lan, Zhenzhong
contents The integration of artificial intelligence in medical imaging has shown tremendous potential, yet the relationship between pre-trained knowledge and performance in cross-modality learning remains unclear. This study investigates how explicitly injecting medical knowledge into the learning process affects the performance of cross-modality classification, focusing on Chest X-ray (CXR) images. We introduce a novel Set Theory-based knowledge injection framework that generates captions for CXR images with controllable knowledge granularity. Using this framework, we fine-tune CLIP model on captions with varying levels of medical information. We evaluate the model's performance through zero-shot classification on the CheXpert dataset, a benchmark for CXR classification. Our results demonstrate that injecting fine-grained medical knowledge substantially improves classification accuracy, achieving 72.5\% compared to 49.9\% when using human-generated captions. This highlights the crucial role of domain-specific knowledge in medical cross-modality learning. Furthermore, we explore the influence of knowledge density and the use of domain-specific Large Language Models (LLMs) for caption generation, finding that denser knowledge and specialized LLMs contribute to enhanced performance. This research advances medical image analysis by demonstrating the effectiveness of knowledge injection for improving automated CXR classification, paving the way for more accurate and reliable diagnostic tools.
format Preprint
id arxiv_https___arxiv_org_abs_2502_13447
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Enhancing Chest X-ray Classification through Knowledge Injection in Cross-Modality Learning
Yan, Yang
Yue, Bingqing
Li, Qiaxuan
Huang, Man
Chen, Jingyu
Lan, Zhenzhong
Computer Vision and Pattern Recognition
Computation and Language
The integration of artificial intelligence in medical imaging has shown tremendous potential, yet the relationship between pre-trained knowledge and performance in cross-modality learning remains unclear. This study investigates how explicitly injecting medical knowledge into the learning process affects the performance of cross-modality classification, focusing on Chest X-ray (CXR) images. We introduce a novel Set Theory-based knowledge injection framework that generates captions for CXR images with controllable knowledge granularity. Using this framework, we fine-tune CLIP model on captions with varying levels of medical information. We evaluate the model's performance through zero-shot classification on the CheXpert dataset, a benchmark for CXR classification. Our results demonstrate that injecting fine-grained medical knowledge substantially improves classification accuracy, achieving 72.5\% compared to 49.9\% when using human-generated captions. This highlights the crucial role of domain-specific knowledge in medical cross-modality learning. Furthermore, we explore the influence of knowledge density and the use of domain-specific Large Language Models (LLMs) for caption generation, finding that denser knowledge and specialized LLMs contribute to enhanced performance. This research advances medical image analysis by demonstrating the effectiveness of knowledge injection for improving automated CXR classification, paving the way for more accurate and reliable diagnostic tools.
title Enhancing Chest X-ray Classification through Knowledge Injection in Cross-Modality Learning
topic Computer Vision and Pattern Recognition
Computation and Language
url https://arxiv.org/abs/2502.13447