ProMedTS: A Self-Supervised, Prompt-Guided Multimodal Approach for Integrating Medical Text and Time Series

Fuente: arXiv
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Hauptverfasser: Niu, Shuai, Ma, Jing, Lin, Hongzhan, Bai, Liang, Wang, Zhihua, Bi, Wei, Xu, Yida, Li, Guo, Yang, Xian
Format: Preprint
Veröffentlicht: 2025
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author Niu, Shuai
Ma, Jing
Lin, Hongzhan
Bai, Liang
Wang, Zhihua
Bi, Wei
Xu, Yida
Li, Guo
Yang, Xian
author_facet Niu, Shuai
Ma, Jing
Lin, Hongzhan
Bai, Liang
Wang, Zhihua
Bi, Wei
Xu, Yida
Li, Guo
Yang, Xian
contents Large language models (LLMs) have shown remarkable performance in vision-language tasks, but their application in the medical field remains underexplored, particularly for integrating structured time series data with unstructured clinical notes. In clinical practice, dynamic time series data, such as lab test results, capture critical temporal patterns, while clinical notes provide rich semantic context. Merging these modalities is challenging due to the inherent differences between continuous signals and discrete text. To bridge this gap, we introduce ProMedTS, a novel self-supervised multimodal framework that employs prompt-guided learning to unify these heterogeneous data types. Our approach leverages lightweight anomaly detection to generate anomaly captions that serve as prompts, guiding the encoding of raw time series data into informative prompt embeddings. These prompt embeddings are aligned with textual representations in a shared latent space, preserving fine-grained temporal nuances alongside semantic insights. Furthermore, our framework incorporates tailored self-supervised objectives to enhance both intra- and inter-modal alignment. We evaluate ProMedTS on disease diagnosis tasks using real-world datasets, and the results demonstrate that our method consistently outperforms state-of-the-art approaches.
format Preprint
id arxiv_https___arxiv_org_abs_2502_13509
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle ProMedTS: A Self-Supervised, Prompt-Guided Multimodal Approach for Integrating Medical Text and Time Series
Niu, Shuai
Ma, Jing
Lin, Hongzhan
Bai, Liang
Wang, Zhihua
Bi, Wei
Xu, Yida
Li, Guo
Yang, Xian
Computation and Language
Artificial Intelligence
Machine Learning
68T50
I.2.7
Large language models (LLMs) have shown remarkable performance in vision-language tasks, but their application in the medical field remains underexplored, particularly for integrating structured time series data with unstructured clinical notes. In clinical practice, dynamic time series data, such as lab test results, capture critical temporal patterns, while clinical notes provide rich semantic context. Merging these modalities is challenging due to the inherent differences between continuous signals and discrete text. To bridge this gap, we introduce ProMedTS, a novel self-supervised multimodal framework that employs prompt-guided learning to unify these heterogeneous data types. Our approach leverages lightweight anomaly detection to generate anomaly captions that serve as prompts, guiding the encoding of raw time series data into informative prompt embeddings. These prompt embeddings are aligned with textual representations in a shared latent space, preserving fine-grained temporal nuances alongside semantic insights. Furthermore, our framework incorporates tailored self-supervised objectives to enhance both intra- and inter-modal alignment. We evaluate ProMedTS on disease diagnosis tasks using real-world datasets, and the results demonstrate that our method consistently outperforms state-of-the-art approaches.
title ProMedTS: A Self-Supervised, Prompt-Guided Multimodal Approach for Integrating Medical Text and Time Series
topic Computation and Language
Artificial Intelligence
Machine Learning
68T50
I.2.7
url https://arxiv.org/abs/2502.13509