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Main Authors: Tivnan, Matthew, Gupta, Amar, Yang, Kai, Wu, Dufan, Gupta, Rajiv
Format: Preprint
Published: 2025
Subjects:
Online Access:https://arxiv.org/abs/2502.15060
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author Tivnan, Matthew
Gupta, Amar
Yang, Kai
Wu, Dufan
Gupta, Rajiv
author_facet Tivnan, Matthew
Gupta, Amar
Yang, Kai
Wu, Dufan
Gupta, Rajiv
contents Multi-source static Computed Tomography (CT) systems have introduced novel opportunities for adaptive imaging techniques. This work presents an innovative method of fluence field modulation using spotlight collimators. These instruments block positive or negative fan angles of even and odd indexed sources, respectively. Spotlight collimators enable volume of interest imaging by increasing relative exposure for the overlapping views. To achieve high quality reconstructions from sparse-view low-dose data, we introduce a generative reconstruction algorithm called Langevin Posterior Sampling (LPS), which uses a score based diffusion prior and physics based likelihood model to sample a posterior random walk. We conduct simulation-based experiments of head CT imaging for stroke detection and we demonstrate that spotlight collimators can effectively reduce the standard deviation and worst-case scenario hallucinations in reconstructed images. Compared to uniform fluence, our approach shows a significant reduction in posterior standard deviation. This highlights the potential for spotlight collimators and generative reconstructions to improve image quality and diagnostic accuracy of multi-source static CT.
format Preprint
id arxiv_https___arxiv_org_abs_2502_15060
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Multi-Source Static CT with Adaptive Fluence Modulation to Minimize Hallucinations in Generative Reconstructions
Tivnan, Matthew
Gupta, Amar
Yang, Kai
Wu, Dufan
Gupta, Rajiv
Medical Physics
Multi-source static Computed Tomography (CT) systems have introduced novel opportunities for adaptive imaging techniques. This work presents an innovative method of fluence field modulation using spotlight collimators. These instruments block positive or negative fan angles of even and odd indexed sources, respectively. Spotlight collimators enable volume of interest imaging by increasing relative exposure for the overlapping views. To achieve high quality reconstructions from sparse-view low-dose data, we introduce a generative reconstruction algorithm called Langevin Posterior Sampling (LPS), which uses a score based diffusion prior and physics based likelihood model to sample a posterior random walk. We conduct simulation-based experiments of head CT imaging for stroke detection and we demonstrate that spotlight collimators can effectively reduce the standard deviation and worst-case scenario hallucinations in reconstructed images. Compared to uniform fluence, our approach shows a significant reduction in posterior standard deviation. This highlights the potential for spotlight collimators and generative reconstructions to improve image quality and diagnostic accuracy of multi-source static CT.
title Multi-Source Static CT with Adaptive Fluence Modulation to Minimize Hallucinations in Generative Reconstructions
topic Medical Physics
url https://arxiv.org/abs/2502.15060