Pub-Guard-LLM: Detecting Retracted Biomedical Articles with Reliable Explanations

Fuente: arXiv
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Autori principali: Chen, Lihu, Fu, Shuojie, Freedman, Gabriel, Zor, Cemre, Martin, Guy, Kinross, James, Vaghela, Uddhav, Serban, Ovidiu, Toni, Francesca
Natura: Preprint
Pubblicazione: 2025
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author Chen, Lihu
Fu, Shuojie
Freedman, Gabriel
Zor, Cemre
Martin, Guy
Kinross, James
Vaghela, Uddhav
Serban, Ovidiu
Toni, Francesca
author_facet Chen, Lihu
Fu, Shuojie
Freedman, Gabriel
Zor, Cemre
Martin, Guy
Kinross, James
Vaghela, Uddhav
Serban, Ovidiu
Toni, Francesca
contents A significant and growing number of published scientific articles is found to involve fraudulent practices, posing a serious threat to the credibility and safety of research in fields such as medicine. We propose Pub-Guard-LLM, the first large language model-based system tailored to fraud detection of biomedical scientific articles. We provide three application modes for deploying Pub-Guard-LLM: vanilla reasoning, retrieval-augmented generation, and multi-agent debate. Each mode allows for textual explanations of predictions. To assess the performance of our system, we introduce an open-source benchmark, PubMed Retraction, comprising over 11K real-world biomedical articles, including metadata and retraction labels. We show that, across all modes, Pub-Guard-LLM consistently surpasses the performance of various baselines and provides more reliable explanations, namely explanations which are deemed more relevant and coherent than those generated by the baselines when evaluated by multiple assessment methods. By enhancing both detection performance and explainability in scientific fraud detection, Pub-Guard-LLM contributes to safeguarding research integrity with a novel, effective, open-source tool.
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id arxiv_https___arxiv_org_abs_2502_15429
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Pub-Guard-LLM: Detecting Retracted Biomedical Articles with Reliable Explanations
Chen, Lihu
Fu, Shuojie
Freedman, Gabriel
Zor, Cemre
Martin, Guy
Kinross, James
Vaghela, Uddhav
Serban, Ovidiu
Toni, Francesca
Computation and Language
A significant and growing number of published scientific articles is found to involve fraudulent practices, posing a serious threat to the credibility and safety of research in fields such as medicine. We propose Pub-Guard-LLM, the first large language model-based system tailored to fraud detection of biomedical scientific articles. We provide three application modes for deploying Pub-Guard-LLM: vanilla reasoning, retrieval-augmented generation, and multi-agent debate. Each mode allows for textual explanations of predictions. To assess the performance of our system, we introduce an open-source benchmark, PubMed Retraction, comprising over 11K real-world biomedical articles, including metadata and retraction labels. We show that, across all modes, Pub-Guard-LLM consistently surpasses the performance of various baselines and provides more reliable explanations, namely explanations which are deemed more relevant and coherent than those generated by the baselines when evaluated by multiple assessment methods. By enhancing both detection performance and explainability in scientific fraud detection, Pub-Guard-LLM contributes to safeguarding research integrity with a novel, effective, open-source tool.
title Pub-Guard-LLM: Detecting Retracted Biomedical Articles with Reliable Explanations
topic Computation and Language
url https://arxiv.org/abs/2502.15429