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Main Authors: Kon, Patrick Tser Jern, Liu, Jiachen, Ding, Qiuyi, Qiu, Yiming, Yang, Zhenning, Huang, Yibo, Srinivasa, Jayanth, Lee, Myungjin, Chowdhury, Mosharaf, Chen, Ang
Format: Preprint
Published: 2025
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Online Access:https://arxiv.org/abs/2502.16069
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author Kon, Patrick Tser Jern
Liu, Jiachen
Ding, Qiuyi
Qiu, Yiming
Yang, Zhenning
Huang, Yibo
Srinivasa, Jayanth
Lee, Myungjin
Chowdhury, Mosharaf
Chen, Ang
author_facet Kon, Patrick Tser Jern
Liu, Jiachen
Ding, Qiuyi
Qiu, Yiming
Yang, Zhenning
Huang, Yibo
Srinivasa, Jayanth
Lee, Myungjin
Chowdhury, Mosharaf
Chen, Ang
contents Scientific experimentation, a cornerstone of human progress, demands rigor in reliability, methodical control, and interpretability to yield meaningful results. Despite the growing capabilities of large language models (LLMs) in automating different aspects of the scientific process, automating rigorous experimentation remains a significant challenge. To address this gap, we propose Curie, an AI agent framework designed to embed rigor into the experimentation process through three key components: an intra-agent rigor module to enhance reliability, an inter-agent rigor module to maintain methodical control, and an experiment knowledge module to enhance interpretability. To evaluate Curie, we design a novel experimental benchmark composed of 46 questions across four computer science domains, derived from influential research papers, and widely adopted open-source projects. Compared to the strongest baseline tested, we achieve a 3.4$\times$ improvement in correctly answering experimental questions. Curie is open-sourced at https://github.com/Just-Curieous/Curie.
format Preprint
id arxiv_https___arxiv_org_abs_2502_16069
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Curie: Toward Rigorous and Automated Scientific Experimentation with AI Agents
Kon, Patrick Tser Jern
Liu, Jiachen
Ding, Qiuyi
Qiu, Yiming
Yang, Zhenning
Huang, Yibo
Srinivasa, Jayanth
Lee, Myungjin
Chowdhury, Mosharaf
Chen, Ang
Artificial Intelligence
Machine Learning
Scientific experimentation, a cornerstone of human progress, demands rigor in reliability, methodical control, and interpretability to yield meaningful results. Despite the growing capabilities of large language models (LLMs) in automating different aspects of the scientific process, automating rigorous experimentation remains a significant challenge. To address this gap, we propose Curie, an AI agent framework designed to embed rigor into the experimentation process through three key components: an intra-agent rigor module to enhance reliability, an inter-agent rigor module to maintain methodical control, and an experiment knowledge module to enhance interpretability. To evaluate Curie, we design a novel experimental benchmark composed of 46 questions across four computer science domains, derived from influential research papers, and widely adopted open-source projects. Compared to the strongest baseline tested, we achieve a 3.4$\times$ improvement in correctly answering experimental questions. Curie is open-sourced at https://github.com/Just-Curieous/Curie.
title Curie: Toward Rigorous and Automated Scientific Experimentation with AI Agents
topic Artificial Intelligence
Machine Learning
url https://arxiv.org/abs/2502.16069