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Hauptverfasser: Thummerer, Adrian, van der Bijl, Erik, Galapon, Arthur Jr, Kamp, Florian, Savenije, Mark, Muijs, Christina, Aluwini, Shafak, Steenbakkers, Roel J. H. M., Beuel, Stephanie, Intven, Martijn P. W., Langendijk, Johannes A., Both, Stefan, Corradini, Stefanie, Rogowski, Viktor, Terpstra, Maarten, Wahl, Niklas, Kurz, Christopher, Landry, Guillaume, Maspero, Matteo
Format: Preprint
Veröffentlicht: 2025
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Online-Zugang:https://arxiv.org/abs/2502.17609
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author Thummerer, Adrian
van der Bijl, Erik
Galapon, Arthur Jr
Kamp, Florian
Savenije, Mark
Muijs, Christina
Aluwini, Shafak
Steenbakkers, Roel J. H. M.
Beuel, Stephanie
Intven, Martijn P. W.
Langendijk, Johannes A.
Both, Stefan
Corradini, Stefanie
Rogowski, Viktor
Terpstra, Maarten
Wahl, Niklas
Kurz, Christopher
Landry, Guillaume
Maspero, Matteo
author_facet Thummerer, Adrian
van der Bijl, Erik
Galapon, Arthur Jr
Kamp, Florian
Savenije, Mark
Muijs, Christina
Aluwini, Shafak
Steenbakkers, Roel J. H. M.
Beuel, Stephanie
Intven, Martijn P. W.
Langendijk, Johannes A.
Both, Stefan
Corradini, Stefanie
Rogowski, Viktor
Terpstra, Maarten
Wahl, Niklas
Kurz, Christopher
Landry, Guillaume
Maspero, Matteo
contents Medical imaging is essential in modern radiotherapy, supporting diagnosis, treatment planning, and monitoring. Synthetic imaging, particularly synthetic computed tomography (sCT), is gaining traction in radiotherapy. The SynthRAD2025 dataset and Grand Challenge promote advancements in sCT generation by providing a benchmarking platform for algorithms using cone-beam CT (CBCT) and magnetic resonance imaging (MRI). The dataset includes 2362 cases: 890 MRI-CT and 1472 CBCT-CT pairs from head-and-neck, thoracic, and abdominal cancer patients treated at five European university medical centers (UMC Groningen, UMC Utrecht, Radboud UMC, LMU University Hospital Munich, and University Hospital of Cologne). Data were acquired with diverse scanners and protocols. Pre-processing, including rigid and deformable image registration, ensures high-quality, modality-aligned images. Extensive quality assurance validates image consistency and usability. All imaging data is provided in MetaImage (.mha) format, ensuring compatibility with medical image processing tools. Metadata, including acquisition parameters and registration details, is available in structured CSV files. To maintain dataset integrity, SynthRAD2025 is divided into training (65%), validation (10%), and test (25%) sets. The dataset is accessible at https://doi.org/10.5281/zenodo.14918089 under the SynthRAD2025 collection. This dataset supports benchmarking and the development of synthetic imaging techniques for radiotherapy applications. Use cases include sCT generation for MRI-only and MR-guided photon/proton therapy, CBCT-based dose calculations, and adaptive radiotherapy workflows. By integrating diverse acquisition settings, SynthRAD2025 fosters robust, generalizable image synthesis algorithms, advancing personalized cancer care and adaptive radiotherapy.
format Preprint
id arxiv_https___arxiv_org_abs_2502_17609
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle SynthRAD2025 Grand Challenge dataset: generating synthetic CTs for radiotherapy
Thummerer, Adrian
van der Bijl, Erik
Galapon, Arthur Jr
Kamp, Florian
Savenije, Mark
Muijs, Christina
Aluwini, Shafak
Steenbakkers, Roel J. H. M.
Beuel, Stephanie
Intven, Martijn P. W.
Langendijk, Johannes A.
Both, Stefan
Corradini, Stefanie
Rogowski, Viktor
Terpstra, Maarten
Wahl, Niklas
Kurz, Christopher
Landry, Guillaume
Maspero, Matteo
Medical Physics
Artificial Intelligence
Computer Vision and Pattern Recognition
Image and Video Processing
Medical imaging is essential in modern radiotherapy, supporting diagnosis, treatment planning, and monitoring. Synthetic imaging, particularly synthetic computed tomography (sCT), is gaining traction in radiotherapy. The SynthRAD2025 dataset and Grand Challenge promote advancements in sCT generation by providing a benchmarking platform for algorithms using cone-beam CT (CBCT) and magnetic resonance imaging (MRI). The dataset includes 2362 cases: 890 MRI-CT and 1472 CBCT-CT pairs from head-and-neck, thoracic, and abdominal cancer patients treated at five European university medical centers (UMC Groningen, UMC Utrecht, Radboud UMC, LMU University Hospital Munich, and University Hospital of Cologne). Data were acquired with diverse scanners and protocols. Pre-processing, including rigid and deformable image registration, ensures high-quality, modality-aligned images. Extensive quality assurance validates image consistency and usability. All imaging data is provided in MetaImage (.mha) format, ensuring compatibility with medical image processing tools. Metadata, including acquisition parameters and registration details, is available in structured CSV files. To maintain dataset integrity, SynthRAD2025 is divided into training (65%), validation (10%), and test (25%) sets. The dataset is accessible at https://doi.org/10.5281/zenodo.14918089 under the SynthRAD2025 collection. This dataset supports benchmarking and the development of synthetic imaging techniques for radiotherapy applications. Use cases include sCT generation for MRI-only and MR-guided photon/proton therapy, CBCT-based dose calculations, and adaptive radiotherapy workflows. By integrating diverse acquisition settings, SynthRAD2025 fosters robust, generalizable image synthesis algorithms, advancing personalized cancer care and adaptive radiotherapy.
title SynthRAD2025 Grand Challenge dataset: generating synthetic CTs for radiotherapy
topic Medical Physics
Artificial Intelligence
Computer Vision and Pattern Recognition
Image and Video Processing
url https://arxiv.org/abs/2502.17609