DeepSeek-R1 Outperforms Gemini 2.0 Pro, OpenAI o1, and o3-mini in Bilingual Complex Ophthalmology Reasoning

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Main Authors: Xu, Pusheng, Wu, Yue, Jin, Kai, Chen, Xiaolan, He, Mingguang, Shi, Danli
Format: Preprint
Published: 2025
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author Xu, Pusheng
Wu, Yue
Jin, Kai
Chen, Xiaolan
He, Mingguang
Shi, Danli
author_facet Xu, Pusheng
Wu, Yue
Jin, Kai
Chen, Xiaolan
He, Mingguang
Shi, Danli
contents Purpose: To evaluate the accuracy and reasoning ability of DeepSeek-R1 and three other recently released large language models (LLMs) in bilingual complex ophthalmology cases. Methods: A total of 130 multiple-choice questions (MCQs) related to diagnosis (n = 39) and management (n = 91) were collected from the Chinese ophthalmology senior professional title examination and categorized into six topics. These MCQs were translated into English using DeepSeek-R1. The responses of DeepSeek-R1, Gemini 2.0 Pro, OpenAI o1 and o3-mini were generated under default configurations between February 15 and February 20, 2025. Accuracy was calculated as the proportion of correctly answered questions, with omissions and extra answers considered incorrect. Reasoning ability was evaluated through analyzing reasoning logic and the causes of reasoning error. Results: DeepSeek-R1 demonstrated the highest overall accuracy, achieving 0.862 in Chinese MCQs and 0.808 in English MCQs. Gemini 2.0 Pro, OpenAI o1, and OpenAI o3-mini attained accuracies of 0.715, 0.685, and 0.692 in Chinese MCQs (all P<0.001 compared with DeepSeek-R1), and 0.746 (P=0.115), 0.723 (P=0.027), and 0.577 (P<0.001) in English MCQs, respectively. DeepSeek-R1 achieved the highest accuracy across five topics in both Chinese and English MCQs. It also excelled in management questions conducted in Chinese (all P<0.05). Reasoning ability analysis showed that the four LLMs shared similar reasoning logic. Ignoring key positive history, ignoring key positive signs, misinterpretation medical data, and too aggressive were the most common causes of reasoning errors. Conclusion: DeepSeek-R1 demonstrated superior performance in bilingual complex ophthalmology reasoning tasks than three other state-of-the-art LLMs. While its clinical applicability remains challenging, it shows promise for supporting diagnosis and clinical decision-making.
format Preprint
id arxiv_https___arxiv_org_abs_2502_17947
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle DeepSeek-R1 Outperforms Gemini 2.0 Pro, OpenAI o1, and o3-mini in Bilingual Complex Ophthalmology Reasoning
Xu, Pusheng
Wu, Yue
Jin, Kai
Chen, Xiaolan
He, Mingguang
Shi, Danli
Computation and Language
Artificial Intelligence
Performance
Purpose: To evaluate the accuracy and reasoning ability of DeepSeek-R1 and three other recently released large language models (LLMs) in bilingual complex ophthalmology cases. Methods: A total of 130 multiple-choice questions (MCQs) related to diagnosis (n = 39) and management (n = 91) were collected from the Chinese ophthalmology senior professional title examination and categorized into six topics. These MCQs were translated into English using DeepSeek-R1. The responses of DeepSeek-R1, Gemini 2.0 Pro, OpenAI o1 and o3-mini were generated under default configurations between February 15 and February 20, 2025. Accuracy was calculated as the proportion of correctly answered questions, with omissions and extra answers considered incorrect. Reasoning ability was evaluated through analyzing reasoning logic and the causes of reasoning error. Results: DeepSeek-R1 demonstrated the highest overall accuracy, achieving 0.862 in Chinese MCQs and 0.808 in English MCQs. Gemini 2.0 Pro, OpenAI o1, and OpenAI o3-mini attained accuracies of 0.715, 0.685, and 0.692 in Chinese MCQs (all P<0.001 compared with DeepSeek-R1), and 0.746 (P=0.115), 0.723 (P=0.027), and 0.577 (P<0.001) in English MCQs, respectively. DeepSeek-R1 achieved the highest accuracy across five topics in both Chinese and English MCQs. It also excelled in management questions conducted in Chinese (all P<0.05). Reasoning ability analysis showed that the four LLMs shared similar reasoning logic. Ignoring key positive history, ignoring key positive signs, misinterpretation medical data, and too aggressive were the most common causes of reasoning errors. Conclusion: DeepSeek-R1 demonstrated superior performance in bilingual complex ophthalmology reasoning tasks than three other state-of-the-art LLMs. While its clinical applicability remains challenging, it shows promise for supporting diagnosis and clinical decision-making.
title DeepSeek-R1 Outperforms Gemini 2.0 Pro, OpenAI o1, and o3-mini in Bilingual Complex Ophthalmology Reasoning
topic Computation and Language
Artificial Intelligence
Performance
url https://arxiv.org/abs/2502.17947