Uncertainty-aware abstention in medical diagnosis based on medical texts

Fuente: arXiv
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Autori principali: Vazhentsev, Artem, Sviridov, Ivan, Barseghyan, Alvard, Kuzmin, Gleb, Panchenko, Alexander, Nesterov, Aleksandr, Shelmanov, Artem, Panov, Maxim
Natura: Preprint
Pubblicazione: 2025
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author Vazhentsev, Artem
Sviridov, Ivan
Barseghyan, Alvard
Kuzmin, Gleb
Panchenko, Alexander
Nesterov, Aleksandr
Shelmanov, Artem
Panov, Maxim
author_facet Vazhentsev, Artem
Sviridov, Ivan
Barseghyan, Alvard
Kuzmin, Gleb
Panchenko, Alexander
Nesterov, Aleksandr
Shelmanov, Artem
Panov, Maxim
contents This study addresses the critical issue of reliability for AI-assisted medical diagnosis. We focus on the selection prediction approach that allows the diagnosis system to abstain from providing the decision if it is not confident in the diagnosis. Such selective prediction (or abstention) approaches are usually based on the modeling predictive uncertainty of machine learning models involved. This study explores uncertainty quantification in machine learning models for medical text analysis, addressing diverse tasks across multiple datasets. We focus on binary mortality prediction from textual data in MIMIC-III, multi-label medical code prediction using ICD-10 codes from MIMIC-IV, and multi-class classification with a private outpatient visits dataset. Additionally, we analyze mental health datasets targeting depression and anxiety detection, utilizing various text-based sources, such as essays, social media posts, and clinical descriptions. In addition to comparing uncertainty methods, we introduce HUQ-2, a new state-of-the-art method for enhancing reliability in selective prediction tasks. Our results provide a detailed comparison of uncertainty quantification methods. They demonstrate the effectiveness of HUQ-2 in capturing and evaluating uncertainty, paving the way for more reliable and interpretable applications in medical text analysis.
format Preprint
id arxiv_https___arxiv_org_abs_2502_18050
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Uncertainty-aware abstention in medical diagnosis based on medical texts
Vazhentsev, Artem
Sviridov, Ivan
Barseghyan, Alvard
Kuzmin, Gleb
Panchenko, Alexander
Nesterov, Aleksandr
Shelmanov, Artem
Panov, Maxim
Computation and Language
This study addresses the critical issue of reliability for AI-assisted medical diagnosis. We focus on the selection prediction approach that allows the diagnosis system to abstain from providing the decision if it is not confident in the diagnosis. Such selective prediction (or abstention) approaches are usually based on the modeling predictive uncertainty of machine learning models involved. This study explores uncertainty quantification in machine learning models for medical text analysis, addressing diverse tasks across multiple datasets. We focus on binary mortality prediction from textual data in MIMIC-III, multi-label medical code prediction using ICD-10 codes from MIMIC-IV, and multi-class classification with a private outpatient visits dataset. Additionally, we analyze mental health datasets targeting depression and anxiety detection, utilizing various text-based sources, such as essays, social media posts, and clinical descriptions. In addition to comparing uncertainty methods, we introduce HUQ-2, a new state-of-the-art method for enhancing reliability in selective prediction tasks. Our results provide a detailed comparison of uncertainty quantification methods. They demonstrate the effectiveness of HUQ-2 in capturing and evaluating uncertainty, paving the way for more reliable and interpretable applications in medical text analysis.
title Uncertainty-aware abstention in medical diagnosis based on medical texts
topic Computation and Language
url https://arxiv.org/abs/2502.18050