End-to-End Deep Learning for Structural Brain Imaging: A Unified Framework
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arXiv
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| Main Authors: | , , , , , , , |
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| Format: | Preprint |
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2025
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| _version_ | 1866916630397714432 |
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| author | Su, Yao Han, Keqi Zeng, Mingjie Sun, Lichao Zhan, Liang Yang, Carl He, Lifang Kong, Xiangnan |
| author_facet | Su, Yao Han, Keqi Zeng, Mingjie Sun, Lichao Zhan, Liang Yang, Carl He, Lifang Kong, Xiangnan |
| contents | Brain imaging analysis is fundamental in neuroscience, providing valuable insights into brain structure and function. Traditional workflows follow a sequential pipeline-brain extraction, registration, segmentation, parcellation, network generation, and classification-treating each step as an independent task. These methods rely heavily on task-specific training data and expert intervention to correct intermediate errors, making them particularly burdensome for high-dimensional neuroimaging data, where annotations and quality control are costly and time-consuming. We introduce UniBrain, a unified end-to-end framework that integrates all processing steps into a single optimization process, allowing tasks to interact and refine each other. Unlike traditional approaches that require extensive task-specific annotations, UniBrain operates with minimal supervision, leveraging only low-cost labels (i.e., classification and extraction) and a single labeled atlas. By jointly optimizing extraction, registration, segmentation, parcellation, network generation, and classification, UniBrain enhances both accuracy and computational efficiency while significantly reducing annotation effort. Experimental results demonstrate its superiority over existing methods across multiple tasks, offering a more scalable and reliable solution for neuroimaging analysis. Our code and data can be found at https://github.com/Anonymous7852/UniBrain |
| format | Preprint |
| id |
arxiv_https___arxiv_org_abs_2502_18523 |
| institution | arXiv |
| publishDate | 2025 |
| record_format | arxiv |
| spellingShingle | End-to-End Deep Learning for Structural Brain Imaging: A Unified Framework Su, Yao Han, Keqi Zeng, Mingjie Sun, Lichao Zhan, Liang Yang, Carl He, Lifang Kong, Xiangnan Image and Video Processing Artificial Intelligence Computer Vision and Pattern Recognition Brain imaging analysis is fundamental in neuroscience, providing valuable insights into brain structure and function. Traditional workflows follow a sequential pipeline-brain extraction, registration, segmentation, parcellation, network generation, and classification-treating each step as an independent task. These methods rely heavily on task-specific training data and expert intervention to correct intermediate errors, making them particularly burdensome for high-dimensional neuroimaging data, where annotations and quality control are costly and time-consuming. We introduce UniBrain, a unified end-to-end framework that integrates all processing steps into a single optimization process, allowing tasks to interact and refine each other. Unlike traditional approaches that require extensive task-specific annotations, UniBrain operates with minimal supervision, leveraging only low-cost labels (i.e., classification and extraction) and a single labeled atlas. By jointly optimizing extraction, registration, segmentation, parcellation, network generation, and classification, UniBrain enhances both accuracy and computational efficiency while significantly reducing annotation effort. Experimental results demonstrate its superiority over existing methods across multiple tasks, offering a more scalable and reliable solution for neuroimaging analysis. Our code and data can be found at https://github.com/Anonymous7852/UniBrain |
| title | End-to-End Deep Learning for Structural Brain Imaging: A Unified Framework |
| topic | Image and Video Processing Artificial Intelligence Computer Vision and Pattern Recognition |
| url | https://arxiv.org/abs/2502.18523 |