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Main Authors: del Castillo, Miguel Herencia García, Garcia, Ricardo Moya, Mazón, Manuel Jesús Cerezo, Garcia, Ekaitz Arriola, Fernández-Miranda, Pablo Menéndez
Format: Preprint
Published: 2025
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Online Access:https://arxiv.org/abs/2502.18620
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author del Castillo, Miguel Herencia García
Garcia, Ricardo Moya
Mazón, Manuel Jesús Cerezo
Garcia, Ekaitz Arriola
Fernández-Miranda, Pablo Menéndez
author_facet del Castillo, Miguel Herencia García
Garcia, Ricardo Moya
Mazón, Manuel Jesús Cerezo
Garcia, Ekaitz Arriola
Fernández-Miranda, Pablo Menéndez
contents In this article, we present a Latent Diffusion Model (LDM) for the generation of brain Magnetic Resonance Imaging (MRI), conditioning its generation based on pathology (Healthy, Glioblastoma, Sclerosis, Dementia) and acquisition modality (T1w, T1ce, T2w, Flair, PD). To evaluate the quality of the generated images, the Fréchet Inception Distance (FID) and Multi-Scale Structural Similarity Index (MS-SSIM) metrics were employed. The results indicate that the model generates images with a distribution similar to real ones, maintaining a balance between visual fidelity and diversity. Additionally, the model demonstrates extrapolation capability, enabling the generation of configurations that were not present in the training data. The results validate the potential of the model to increase in the number of samples in clinical datasets, balancing underrepresented classes, and evaluating AI models in medicine, contributing to the development of diagnostic tools in radiology without compromising patient privacy.
format Preprint
id arxiv_https___arxiv_org_abs_2502_18620
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Diffusion Models for conditional MRI generation
del Castillo, Miguel Herencia García
Garcia, Ricardo Moya
Mazón, Manuel Jesús Cerezo
Garcia, Ekaitz Arriola
Fernández-Miranda, Pablo Menéndez
Computer Vision and Pattern Recognition
Artificial Intelligence
Machine Learning
In this article, we present a Latent Diffusion Model (LDM) for the generation of brain Magnetic Resonance Imaging (MRI), conditioning its generation based on pathology (Healthy, Glioblastoma, Sclerosis, Dementia) and acquisition modality (T1w, T1ce, T2w, Flair, PD). To evaluate the quality of the generated images, the Fréchet Inception Distance (FID) and Multi-Scale Structural Similarity Index (MS-SSIM) metrics were employed. The results indicate that the model generates images with a distribution similar to real ones, maintaining a balance between visual fidelity and diversity. Additionally, the model demonstrates extrapolation capability, enabling the generation of configurations that were not present in the training data. The results validate the potential of the model to increase in the number of samples in clinical datasets, balancing underrepresented classes, and evaluating AI models in medicine, contributing to the development of diagnostic tools in radiology without compromising patient privacy.
title Diffusion Models for conditional MRI generation
topic Computer Vision and Pattern Recognition
Artificial Intelligence
Machine Learning
url https://arxiv.org/abs/2502.18620