Ptychographic Image Reconstruction from Limited Data via Score-Based Diffusion Models with Physics-Guidance

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Hauptverfasser: Cam, Refik Mert, Deng, Junjing, Kettimuthu, Rajkumar, Cherukara, Mathew J., Bicer, Tekin
Format: Preprint
Veröffentlicht: 2025
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author Cam, Refik Mert
Deng, Junjing
Kettimuthu, Rajkumar
Cherukara, Mathew J.
Bicer, Tekin
author_facet Cam, Refik Mert
Deng, Junjing
Kettimuthu, Rajkumar
Cherukara, Mathew J.
Bicer, Tekin
contents Ptychography is a data-intensive computational imaging technique that achieves high spatial resolution over large fields of view. The technique involves scanning a coherent beam across overlapping regions and recording diffraction patterns. Conventional reconstruction algorithms require substantial overlap, increasing data volume and experimental time, reaching PiB-scale experimental data and weeks to month-long data acquisition times. To address this, we propose a reconstruction method employing a physics-guided score-based diffusion model. Our approach trains a diffusion model on representative object images to learn an object distribution prior. During reconstruction, we modify the reverse diffusion process to enforce data consistency, guiding reverse diffusion toward a physically plausible solution. This method requires a single pretraining phase, allowing it to generalize across varying scan overlap ratios and positions. Our results demonstrate that the proposed method achieves high-fidelity reconstructions with only a 20% overlap, while the widely employed rPIE method requires a 62% overlap to achieve similar accuracy. This represents a significant reduction in data requirements, offering an alternative to conventional techniques.
format Preprint
id arxiv_https___arxiv_org_abs_2502_18767
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Ptychographic Image Reconstruction from Limited Data via Score-Based Diffusion Models with Physics-Guidance
Cam, Refik Mert
Deng, Junjing
Kettimuthu, Rajkumar
Cherukara, Mathew J.
Bicer, Tekin
Image and Video Processing
Ptychography is a data-intensive computational imaging technique that achieves high spatial resolution over large fields of view. The technique involves scanning a coherent beam across overlapping regions and recording diffraction patterns. Conventional reconstruction algorithms require substantial overlap, increasing data volume and experimental time, reaching PiB-scale experimental data and weeks to month-long data acquisition times. To address this, we propose a reconstruction method employing a physics-guided score-based diffusion model. Our approach trains a diffusion model on representative object images to learn an object distribution prior. During reconstruction, we modify the reverse diffusion process to enforce data consistency, guiding reverse diffusion toward a physically plausible solution. This method requires a single pretraining phase, allowing it to generalize across varying scan overlap ratios and positions. Our results demonstrate that the proposed method achieves high-fidelity reconstructions with only a 20% overlap, while the widely employed rPIE method requires a 62% overlap to achieve similar accuracy. This represents a significant reduction in data requirements, offering an alternative to conventional techniques.
title Ptychographic Image Reconstruction from Limited Data via Score-Based Diffusion Models with Physics-Guidance
topic Image and Video Processing
url https://arxiv.org/abs/2502.18767