Overcoming Dependent Censoring in the Evaluation of Survival Models

Fuente: arXiv
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Autores principales: Lillelund, Christian Marius, Qi, Shi-ang, Greiner, Russell
Formato: Preprint
Publicado: 2025
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author Lillelund, Christian Marius
Qi, Shi-ang
Greiner, Russell
author_facet Lillelund, Christian Marius
Qi, Shi-ang
Greiner, Russell
contents Conventional survival metrics, such as Harrell's concordance index (CI) and the Brier Score, rely on the independent censoring assumption for valid inference with right-censored data. However, in the presence of so-called dependent censoring, where the probability of censoring is related to the event of interest, these metrics can give biased estimates of the underlying model error. In this paper, we introduce three new evaluation metrics for survival analysis based on Archimedean copulas that can account for dependent censoring. We also develop a framework to generate realistic, semi-synthetic datasets with dependent censoring to facilitate the evaluation of the metrics. Our experiments in synthetic and semi-synthetic data demonstrate that the proposed metrics can provide more accurate estimates of the model error than conventional metrics under dependent censoring.
format Preprint
id arxiv_https___arxiv_org_abs_2502_19460
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Overcoming Dependent Censoring in the Evaluation of Survival Models
Lillelund, Christian Marius
Qi, Shi-ang
Greiner, Russell
Machine Learning
Artificial Intelligence
Conventional survival metrics, such as Harrell's concordance index (CI) and the Brier Score, rely on the independent censoring assumption for valid inference with right-censored data. However, in the presence of so-called dependent censoring, where the probability of censoring is related to the event of interest, these metrics can give biased estimates of the underlying model error. In this paper, we introduce three new evaluation metrics for survival analysis based on Archimedean copulas that can account for dependent censoring. We also develop a framework to generate realistic, semi-synthetic datasets with dependent censoring to facilitate the evaluation of the metrics. Our experiments in synthetic and semi-synthetic data demonstrate that the proposed metrics can provide more accurate estimates of the model error than conventional metrics under dependent censoring.
title Overcoming Dependent Censoring in the Evaluation of Survival Models
topic Machine Learning
Artificial Intelligence
url https://arxiv.org/abs/2502.19460