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Main Authors: Cappello, Franck, Madireddy, Sandeep, Underwood, Robert, Getty, Neil, Chia, Nicholas Lee-Ping, Ramachandra, Nesar, Nguyen, Josh, Keceli, Murat, Mallick, Tanwi, Li, Zilinghan, Ngom, Marieme, Zhang, Chenhui, Yanguas-Gil, Angel, Antoniuk, Evan, Kailkhura, Bhavya, Tian, Minyang, Du, Yufeng, Ting, Yuan-Sen, Wells, Azton, Nicolae, Bogdan, Maurya, Avinash, Rafique, M. Mustafa, Huerta, Eliu, Li, Bo, Foster, Ian, Stevens, Rick
Format: Preprint
Published: 2025
Subjects:
Online Access:https://arxiv.org/abs/2502.20309
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author Cappello, Franck
Madireddy, Sandeep
Underwood, Robert
Getty, Neil
Chia, Nicholas Lee-Ping
Ramachandra, Nesar
Nguyen, Josh
Keceli, Murat
Mallick, Tanwi
Li, Zilinghan
Ngom, Marieme
Zhang, Chenhui
Yanguas-Gil, Angel
Antoniuk, Evan
Kailkhura, Bhavya
Tian, Minyang
Du, Yufeng
Ting, Yuan-Sen
Wells, Azton
Nicolae, Bogdan
Maurya, Avinash
Rafique, M. Mustafa
Huerta, Eliu
Li, Bo
Foster, Ian
Stevens, Rick
author_facet Cappello, Franck
Madireddy, Sandeep
Underwood, Robert
Getty, Neil
Chia, Nicholas Lee-Ping
Ramachandra, Nesar
Nguyen, Josh
Keceli, Murat
Mallick, Tanwi
Li, Zilinghan
Ngom, Marieme
Zhang, Chenhui
Yanguas-Gil, Angel
Antoniuk, Evan
Kailkhura, Bhavya
Tian, Minyang
Du, Yufeng
Ting, Yuan-Sen
Wells, Azton
Nicolae, Bogdan
Maurya, Avinash
Rafique, M. Mustafa
Huerta, Eliu
Li, Bo
Foster, Ian
Stevens, Rick
contents Recent advancements have positioned AI, and particularly Large Language Models (LLMs), as transformative tools for scientific research, capable of addressing complex tasks that require reasoning, problem-solving, and decision-making. Their exceptional capabilities suggest their potential as scientific research assistants but also highlight the need for holistic, rigorous, and domain-specific evaluation to assess effectiveness in real-world scientific applications. This paper describes a multifaceted methodology for Evaluating AI models as scientific Research Assistants (EAIRA) developed at Argonne National Laboratory. This methodology incorporates four primary classes of evaluations. 1) Multiple Choice Questions to assess factual recall; 2) Open Response to evaluate advanced reasoning and problem-solving skills; 3) Lab-Style Experiments involving detailed analysis of capabilities as research assistants in controlled environments; and 4) Field-Style Experiments to capture researcher-LLM interactions at scale in a wide range of scientific domains and applications. These complementary methods enable a comprehensive analysis of LLM strengths and weaknesses with respect to their scientific knowledge, reasoning abilities, and adaptability. Recognizing the rapid pace of LLM advancements, we designed the methodology to evolve and adapt so as to ensure its continued relevance and applicability. This paper describes the methodology state at the end of February 2025. Although developed within a subset of scientific domains, the methodology is designed to be generalizable to a wide range of scientific domains.
format Preprint
id arxiv_https___arxiv_org_abs_2502_20309
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle EAIRA: Establishing a Methodology for Evaluating AI Models as Scientific Research Assistants
Cappello, Franck
Madireddy, Sandeep
Underwood, Robert
Getty, Neil
Chia, Nicholas Lee-Ping
Ramachandra, Nesar
Nguyen, Josh
Keceli, Murat
Mallick, Tanwi
Li, Zilinghan
Ngom, Marieme
Zhang, Chenhui
Yanguas-Gil, Angel
Antoniuk, Evan
Kailkhura, Bhavya
Tian, Minyang
Du, Yufeng
Ting, Yuan-Sen
Wells, Azton
Nicolae, Bogdan
Maurya, Avinash
Rafique, M. Mustafa
Huerta, Eliu
Li, Bo
Foster, Ian
Stevens, Rick
Artificial Intelligence
Recent advancements have positioned AI, and particularly Large Language Models (LLMs), as transformative tools for scientific research, capable of addressing complex tasks that require reasoning, problem-solving, and decision-making. Their exceptional capabilities suggest their potential as scientific research assistants but also highlight the need for holistic, rigorous, and domain-specific evaluation to assess effectiveness in real-world scientific applications. This paper describes a multifaceted methodology for Evaluating AI models as scientific Research Assistants (EAIRA) developed at Argonne National Laboratory. This methodology incorporates four primary classes of evaluations. 1) Multiple Choice Questions to assess factual recall; 2) Open Response to evaluate advanced reasoning and problem-solving skills; 3) Lab-Style Experiments involving detailed analysis of capabilities as research assistants in controlled environments; and 4) Field-Style Experiments to capture researcher-LLM interactions at scale in a wide range of scientific domains and applications. These complementary methods enable a comprehensive analysis of LLM strengths and weaknesses with respect to their scientific knowledge, reasoning abilities, and adaptability. Recognizing the rapid pace of LLM advancements, we designed the methodology to evolve and adapt so as to ensure its continued relevance and applicability. This paper describes the methodology state at the end of February 2025. Although developed within a subset of scientific domains, the methodology is designed to be generalizable to a wide range of scientific domains.
title EAIRA: Establishing a Methodology for Evaluating AI Models as Scientific Research Assistants
topic Artificial Intelligence
url https://arxiv.org/abs/2502.20309