Localization of tumor through a non-conventional numerical shape optimization technique

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1. Verfasser: Rabago, Julius Fergy Tiongson
Format: Preprint
Veröffentlicht: 2025
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author Rabago, Julius Fergy Tiongson
author_facet Rabago, Julius Fergy Tiongson
contents This paper introduces a method for estimating the shape and location of an embedded tumor. The approach utilizes shape optimization techniques, applying the coupled complex boundary method. By rewriting the problem -- characterized by a measured temperature profile and corresponding flux (e.g., from infrared thermography) -- into a complex boundary value problem with a complex Robin boundary condition, the method simplifies the over-specified nature of the problem. The size and location of the tumor are identified by optimizing an objective function based on the imaginary part of the solution across the domain. Shape sensitivity analysis is conducted to compute the shape derivative of the functional. An iterative algorithm, which uses the Riesz representative of the gradient, is developed to numerically determine the geometry of the tumor via the finite element method. Additionally, we analyze the mesh sensitivity of the finite element solution of the associated state problem and derive a bound on its variation in terms of mesh deformation and its gradient. Numerical examples are provided to validate the theoretical findings and demonstrate the accuracy and effectiveness of the proposed method.
format Preprint
id arxiv_https___arxiv_org_abs_2502_20656
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Localization of tumor through a non-conventional numerical shape optimization technique
Rabago, Julius Fergy Tiongson
Numerical Analysis
Optimization and Control
49N45, 49Q10, 49K40, 65N21, 65N30, 65N50
This paper introduces a method for estimating the shape and location of an embedded tumor. The approach utilizes shape optimization techniques, applying the coupled complex boundary method. By rewriting the problem -- characterized by a measured temperature profile and corresponding flux (e.g., from infrared thermography) -- into a complex boundary value problem with a complex Robin boundary condition, the method simplifies the over-specified nature of the problem. The size and location of the tumor are identified by optimizing an objective function based on the imaginary part of the solution across the domain. Shape sensitivity analysis is conducted to compute the shape derivative of the functional. An iterative algorithm, which uses the Riesz representative of the gradient, is developed to numerically determine the geometry of the tumor via the finite element method. Additionally, we analyze the mesh sensitivity of the finite element solution of the associated state problem and derive a bound on its variation in terms of mesh deformation and its gradient. Numerical examples are provided to validate the theoretical findings and demonstrate the accuracy and effectiveness of the proposed method.
title Localization of tumor through a non-conventional numerical shape optimization technique
topic Numerical Analysis
Optimization and Control
49N45, 49Q10, 49K40, 65N21, 65N30, 65N50
url https://arxiv.org/abs/2502.20656