MedHallTune: An Instruction-Tuning Benchmark for Mitigating Medical Hallucination in Vision-Language Models

Fuente: arXiv
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Main Authors: Yan, Qiao, Yuan, Yuchen, Hu, Xiaowei, Wang, Yihan, Xu, Jiaqi, Li, Jinpeng, Fu, Chi-Wing, Heng, Pheng-Ann
Format: Preprint
Published: 2025
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author Yan, Qiao
Yuan, Yuchen
Hu, Xiaowei
Wang, Yihan
Xu, Jiaqi
Li, Jinpeng
Fu, Chi-Wing
Heng, Pheng-Ann
author_facet Yan, Qiao
Yuan, Yuchen
Hu, Xiaowei
Wang, Yihan
Xu, Jiaqi
Li, Jinpeng
Fu, Chi-Wing
Heng, Pheng-Ann
contents The increasing use of vision-language models (VLMs) in healthcare applications presents great challenges related to hallucinations, in which the models may generate seemingly plausible results that are in fact incorrect. Such hallucinations can jeopardize clinical decision making, potentially harming the diagnosis and treatments. In this work, we propose MedHallTune, a large-scale benchmark designed specifically to evaluate and mitigate hallucinations in medical VLMs. Comprising over 100,000 images and 1,000,000 instruction pairs, MedHallTune includes both hallucination and non-hallucination samples, each with ground-truth annotations. We conduct a comprehensive evaluation of current medical and general VLMs using MedHallTune, assessing their performance across key metrics, including clinical accuracy, relevance, detail level, and risk level. The experimental results show that fine-tuning with MedHallTune successfully improves the ability of several existing models to manage hallucinations and boost their zero-shot performance on downstream visual-question-answering (VQA) tasks, making them more reliable for practical medical applications. Our work contributes to the development of more trustworthy VLMs. Codes and dataset will be available at \href{https://github.com/russellyq/MedHallTune}{MedHallTune}.
format Preprint
id arxiv_https___arxiv_org_abs_2502_20780
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle MedHallTune: An Instruction-Tuning Benchmark for Mitigating Medical Hallucination in Vision-Language Models
Yan, Qiao
Yuan, Yuchen
Hu, Xiaowei
Wang, Yihan
Xu, Jiaqi
Li, Jinpeng
Fu, Chi-Wing
Heng, Pheng-Ann
Artificial Intelligence
Computation and Language
Computer Vision and Pattern Recognition
The increasing use of vision-language models (VLMs) in healthcare applications presents great challenges related to hallucinations, in which the models may generate seemingly plausible results that are in fact incorrect. Such hallucinations can jeopardize clinical decision making, potentially harming the diagnosis and treatments. In this work, we propose MedHallTune, a large-scale benchmark designed specifically to evaluate and mitigate hallucinations in medical VLMs. Comprising over 100,000 images and 1,000,000 instruction pairs, MedHallTune includes both hallucination and non-hallucination samples, each with ground-truth annotations. We conduct a comprehensive evaluation of current medical and general VLMs using MedHallTune, assessing their performance across key metrics, including clinical accuracy, relevance, detail level, and risk level. The experimental results show that fine-tuning with MedHallTune successfully improves the ability of several existing models to manage hallucinations and boost their zero-shot performance on downstream visual-question-answering (VQA) tasks, making them more reliable for practical medical applications. Our work contributes to the development of more trustworthy VLMs. Codes and dataset will be available at \href{https://github.com/russellyq/MedHallTune}{MedHallTune}.
title MedHallTune: An Instruction-Tuning Benchmark for Mitigating Medical Hallucination in Vision-Language Models
topic Artificial Intelligence
Computation and Language
Computer Vision and Pattern Recognition
url https://arxiv.org/abs/2502.20780