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Bibliographic Details
Main Authors: Hooten, Mason, Patel, Het, Shao, Yiwei, Singh, Rishabh Kumar, Dutt, Meenakshi
Format: Preprint
Published: 2025
Subjects:
Online Access:https://arxiv.org/abs/2502.21148
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Table of Contents:
  • This review article discusses some common enhanced sampling methods in relation to the process of self-assembly of biomolecules. An introduction to self-assembly and its challenges is covered followed by a brief overview of the methods and analysis for replica-exchange molecular dynamics, umbrella sampling, metadynamics, and machine learning based techniques. Applications of select methods towards peptides, proteins, polymers, nucleic acids, and supramolecules are discussed. Finally, a short discussion of the future directions of some of these methods is provided.