Flow Matching for Medical Image Synthesis: Bridging the Gap Between Speed and Quality

Fuente: arXiv
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Main Authors: Yazdani, Milad, Medghalchi, Yasamin, Ashrafian, Pooria, Hacihaliloglu, Ilker, Shahriari, Dena
Format: Preprint
Published: 2025
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author Yazdani, Milad
Medghalchi, Yasamin
Ashrafian, Pooria
Hacihaliloglu, Ilker
Shahriari, Dena
author_facet Yazdani, Milad
Medghalchi, Yasamin
Ashrafian, Pooria
Hacihaliloglu, Ilker
Shahriari, Dena
contents Deep learning models have emerged as a powerful tool for various medical applications. However, their success depends on large, high-quality datasets that are challenging to obtain due to privacy concerns and costly annotation. Generative models, such as diffusion models, offer a potential solution by synthesizing medical images, but their practical adoption is hindered by long inference times. In this paper, we propose the use of an optimal transport flow matching approach to accelerate image generation. By introducing a straighter mapping between the source and target distribution, our method significantly reduces inference time while preserving and further enhancing the quality of the outputs. Furthermore, this approach is highly adaptable, supporting various medical imaging modalities, conditioning mechanisms (such as class labels and masks), and different spatial dimensions, including 2D and 3D. Beyond image generation, it can also be applied to related tasks such as image enhancement. Our results demonstrate the efficiency and versatility of this framework, making it a promising advancement for medical imaging applications. Code with checkpoints and a synthetic dataset (beneficial for classification and segmentation) is now available on: https://github.com/milad1378yz/MOTFM.
format Preprint
id arxiv_https___arxiv_org_abs_2503_00266
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Flow Matching for Medical Image Synthesis: Bridging the Gap Between Speed and Quality
Yazdani, Milad
Medghalchi, Yasamin
Ashrafian, Pooria
Hacihaliloglu, Ilker
Shahriari, Dena
Computer Vision and Pattern Recognition
Image and Video Processing
Deep learning models have emerged as a powerful tool for various medical applications. However, their success depends on large, high-quality datasets that are challenging to obtain due to privacy concerns and costly annotation. Generative models, such as diffusion models, offer a potential solution by synthesizing medical images, but their practical adoption is hindered by long inference times. In this paper, we propose the use of an optimal transport flow matching approach to accelerate image generation. By introducing a straighter mapping between the source and target distribution, our method significantly reduces inference time while preserving and further enhancing the quality of the outputs. Furthermore, this approach is highly adaptable, supporting various medical imaging modalities, conditioning mechanisms (such as class labels and masks), and different spatial dimensions, including 2D and 3D. Beyond image generation, it can also be applied to related tasks such as image enhancement. Our results demonstrate the efficiency and versatility of this framework, making it a promising advancement for medical imaging applications. Code with checkpoints and a synthetic dataset (beneficial for classification and segmentation) is now available on: https://github.com/milad1378yz/MOTFM.
title Flow Matching for Medical Image Synthesis: Bridging the Gap Between Speed and Quality
topic Computer Vision and Pattern Recognition
Image and Video Processing
url https://arxiv.org/abs/2503.00266