T-cell receptor specificity landscape revealed through de novo peptide design
Fuente:
arXiv
Saved in:
| Main Authors: | Visani, Gian Marco, Pun, Michael N., Minervina, Anastasia A., Bradley, Philip, Thomas, Paul, Nourmohammad, Armita |
|---|---|
| Format: | Preprint |
| Published: |
2025
|
| Subjects: | |
| Online Access: | |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
Loop-Diffusion: an equivariant diffusion model for designing and scoring protein loops
by: Borisiak, Kevin, et al.
Published: (2024)
by: Borisiak, Kevin, et al.
Published: (2024)
De novo peptide sequencing rescoring and FDR estimation with Winnow
by: Mabona, Amandla, et al.
Published: (2025)
by: Mabona, Amandla, et al.
Published: (2025)
Mathematical modeling of heterogeneous stem cell regeneration: from cell division to Waddington's epigenetic landscape
by: Lei, Jinzhi
Published: (2023)
by: Lei, Jinzhi
Published: (2023)
tcrLM: a lightweight protein language model for predicting T cell receptor and epitope binding specificity
by: Fang, Xing, et al.
Published: (2024)
by: Fang, Xing, et al.
Published: (2024)
Stochastic modelling reveals that chromatin folding buffers epigenetic landscapes against sirtuin depletion during DNA damage
by: Stepanova, Daria, et al.
Published: (2025)
by: Stepanova, Daria, et al.
Published: (2025)
Transformer-based de novo peptide sequencing for data-independent acquisition mass spectrometry
by: Ebrahimi, Shiva, et al.
Published: (2024)
by: Ebrahimi, Shiva, et al.
Published: (2024)
Artificial Intelligence for CRISPR Guide RNA Design: Explainable Models and Off-Target Safety
by: Abbaszadeh, Alireza, et al.
Published: (2025)
by: Abbaszadeh, Alireza, et al.
Published: (2025)
Timing consistency of T cell receptor activation in a stochastic model combining kinetic segregation and proofreading
by: Prüstel, Thorsten, et al.
Published: (2024)
by: Prüstel, Thorsten, et al.
Published: (2024)
All the single cells: single-cell transcriptomics/epigenomics experimental design and analysis considerations for glial biologists
by: Prater, Katherine E., et al.
Published: (2024)
by: Prater, Katherine E., et al.
Published: (2024)
MULTILAND: a neutral landscape generator designed for theoretical studies
by: Roques, Lionel
Published: (2015)
by: Roques, Lionel
Published: (2015)
CEI: A Clonal Expansion Identifier for T-cell receptor clones following SARS-CoV-2 vaccination
by: Pan, Yunbei, et al.
Published: (2026)
by: Pan, Yunbei, et al.
Published: (2026)
AI-derived layer-specific OCT biomarkers for classification of geographic atrophy
by: Guo, Yukun, et al.
Published: (2025)
by: Guo, Yukun, et al.
Published: (2025)
Uncertainty quantification of receptor ligand binding sites prediction
by: Chen, Nanjie, et al.
Published: (2024)
by: Chen, Nanjie, et al.
Published: (2024)
Learning immune receptor representations with protein language models
by: Dounas, Andreas, et al.
Published: (2024)
by: Dounas, Andreas, et al.
Published: (2024)
T cell receptor binding prediction: A machine learning revolution
by: Weber, Anna, et al.
Published: (2023)
by: Weber, Anna, et al.
Published: (2023)
Synthesizing study-specific controls using generative models on open access datasets for harmonized multi-study analyses
by: Gadewar, Shruti P., et al.
Published: (2024)
by: Gadewar, Shruti P., et al.
Published: (2024)
SERS discrimination of single amino acid residue in single peptide by plasmonic nanocavities
by: Huang, Jian-An, et al.
Published: (2019)
by: Huang, Jian-An, et al.
Published: (2019)
Direct RNA sequence design under codon constraints using expressive tensor-based secondary structure models
by: Fornace, Mark, et al.
Published: (2026)
by: Fornace, Mark, et al.
Published: (2026)
How high-resolution agent-based models can improve fundamental insights in tissue development and cell culturing methods
by: Van Liedekerke, Paul, et al.
Published: (2026)
by: Van Liedekerke, Paul, et al.
Published: (2026)
Using timescale as a state coordinate reveals the metastable geometry of behavior
by: Kaur, Rajpreet, et al.
Published: (2026)
by: Kaur, Rajpreet, et al.
Published: (2026)
LNODE: latent dynamics reveal the shared spatiotemporal structure of amyloid-$β$ progression
by: Wen, Zheyu, et al.
Published: (2026)
by: Wen, Zheyu, et al.
Published: (2026)
Conformational landscapes in cryo-ET data based on MD simulations
by: Jonic, Slavica
Published: (2026)
by: Jonic, Slavica
Published: (2026)
Comparative analysis of computational approaches for predicting Transthyretin (TTR) transcription activators and human dopamine D1 receptor antagonists
by: Ivanova, Mariya L., et al.
Published: (2025)
by: Ivanova, Mariya L., et al.
Published: (2025)
Sample volume as a key design parameter in affinity-based biosensors
by: Beijersbergen, Daan, et al.
Published: (2025)
by: Beijersbergen, Daan, et al.
Published: (2025)
An algorithmic framework for synthetic cost-aware decision making in molecular design
by: Fromer, Jenna C., et al.
Published: (2023)
by: Fromer, Jenna C., et al.
Published: (2023)
The three-dimensional impulse-response model: Modeling the training process in accordance with energy system-specific adaptation
by: Kontro, Hilkka, et al.
Published: (2025)
by: Kontro, Hilkka, et al.
Published: (2025)
Continued domain-specific pre-training of protein language models for pMHC-I binding prediction
by: Mares, Sergio E., et al.
Published: (2025)
by: Mares, Sergio E., et al.
Published: (2025)
Understanding the role of B-cells in CAR T-cell therapy in leukemia through a mathematical model
by: Serrano, Sergio, et al.
Published: (2024)
by: Serrano, Sergio, et al.
Published: (2024)
Cooperative SIR dynamics as a model for spontaneous blood clot initiation
by: Greulich, Philip
Published: (2024)
by: Greulich, Philip
Published: (2024)
Stress distribution in contractile cell monolayers
by: Huo, Yucheng, et al.
Published: (2025)
by: Huo, Yucheng, et al.
Published: (2025)
In silico design, in vitro construction and in vivo application of synthetic small regulatory RNAs in bacteria
by: Brueck, Michel, et al.
Published: (2023)
by: Brueck, Michel, et al.
Published: (2023)
easyplater: The easy way to generate microplate designs deconvolved from multivariate clinical data
by: Taylor, Avigail, et al.
Published: (2025)
by: Taylor, Avigail, et al.
Published: (2025)
Assessing the distribution of cancer stem cells in tumorspheres
by: Fotinós, Jerónimo, et al.
Published: (2024)
by: Fotinós, Jerónimo, et al.
Published: (2024)
Lightning-fast adaptive immune receptor similarity search by symmetric deletion lookup
by: Chotisorayuth, Touchchai, et al.
Published: (2024)
by: Chotisorayuth, Touchchai, et al.
Published: (2024)
A Bayesian approach to model uncertainty in single-cell genomic data
by: Ren, Shanshan, et al.
Published: (2025)
by: Ren, Shanshan, et al.
Published: (2025)
Fixed-budget simulation method for growing cell populations
by: Chen, Shaoqing, et al.
Published: (2025)
by: Chen, Shaoqing, et al.
Published: (2025)
A geometric feature tracking approach for noninvasive patient specific estimation of leaflet strain from 3D images of heart valves
by: Wu, Wensi, et al.
Published: (2025)
by: Wu, Wensi, et al.
Published: (2025)
Spatial information allows inference of the prevalence of direct cell-to-cell viral infection
by: Williams, Thomas, et al.
Published: (2023)
by: Williams, Thomas, et al.
Published: (2023)
Efficient design of rna sequences with desired properties, structure, and motifs using a grammar variational autoencoder
by: Zarnaghinaghsh, Narges, et al.
Published: (2025)
by: Zarnaghinaghsh, Narges, et al.
Published: (2025)
Information-Theoretical Measures for Developmental Cell-Fate Proportioning Processes
by: Ramirez-Sierra, Michael A., et al.
Published: (2025)
by: Ramirez-Sierra, Michael A., et al.
Published: (2025)
Similar Items
-
Loop-Diffusion: an equivariant diffusion model for designing and scoring protein loops
by: Borisiak, Kevin, et al.
Published: (2024) -
De novo peptide sequencing rescoring and FDR estimation with Winnow
by: Mabona, Amandla, et al.
Published: (2025) -
Mathematical modeling of heterogeneous stem cell regeneration: from cell division to Waddington's epigenetic landscape
by: Lei, Jinzhi
Published: (2023) -
tcrLM: a lightweight protein language model for predicting T cell receptor and epitope binding specificity
by: Fang, Xing, et al.
Published: (2024) -
Stochastic modelling reveals that chromatin folding buffers epigenetic landscapes against sirtuin depletion during DNA damage
by: Stepanova, Daria, et al.
Published: (2025)