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Autori principali: Zhang, Jingru, Zhang, Shengjie, Jones, Christopher W, Basner, Mathias, Shou, Haochang
Natura: Preprint
Pubblicazione: 2025
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Accesso online:https://arxiv.org/abs/2503.01514
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author Zhang, Jingru
Zhang, Shengjie
Jones, Christopher W
Basner, Mathias
Shou, Haochang
author_facet Zhang, Jingru
Zhang, Shengjie
Jones, Christopher W
Basner, Mathias
Shou, Haochang
contents Advancements in data collection have led to increasingly common repeated observations with complex structures in biomedical studies. Treating these observations as random objects, rather than summarizing features as vectors, avoids feature extraction and better reflects the data's nature. Examples include repeatedly measured activity intensity distributions in physical activity analysis and brain networks in neuroimaging. Testing whether these repeated random objects differ across groups is fundamentally important; however, traditional statistical tests often face challenges due to the non-Euclidean nature of metric spaces, dependencies from repeated measurements, and the unequal number of repeated measures. By defining within-subject variability using pairwise distances between repeated measures and extending Fréchet analysis of variance, we develop a generalized Fréchet test for exchangeable repeated random objects, applicable to general metric space-valued data with unequal numbers of repeated measures. The proposed test can simultaneously detect differences in location, scale, and within-subject variability. We derive the asymptotic distribution of the test statistic, which follows a weighted chi-squared distribution. Simulations demonstrate that the proposed test performs well across different types of random objects. We illustrate its effectiveness through applications to physical activity data and resting-state functional magnetic resonance imaging data.
format Preprint
id arxiv_https___arxiv_org_abs_2503_01514
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle A Generalized Fréchet Test for Object Data with Unequal Repeated Measurements
Zhang, Jingru
Zhang, Shengjie
Jones, Christopher W
Basner, Mathias
Shou, Haochang
Methodology
Advancements in data collection have led to increasingly common repeated observations with complex structures in biomedical studies. Treating these observations as random objects, rather than summarizing features as vectors, avoids feature extraction and better reflects the data's nature. Examples include repeatedly measured activity intensity distributions in physical activity analysis and brain networks in neuroimaging. Testing whether these repeated random objects differ across groups is fundamentally important; however, traditional statistical tests often face challenges due to the non-Euclidean nature of metric spaces, dependencies from repeated measurements, and the unequal number of repeated measures. By defining within-subject variability using pairwise distances between repeated measures and extending Fréchet analysis of variance, we develop a generalized Fréchet test for exchangeable repeated random objects, applicable to general metric space-valued data with unequal numbers of repeated measures. The proposed test can simultaneously detect differences in location, scale, and within-subject variability. We derive the asymptotic distribution of the test statistic, which follows a weighted chi-squared distribution. Simulations demonstrate that the proposed test performs well across different types of random objects. We illustrate its effectiveness through applications to physical activity data and resting-state functional magnetic resonance imaging data.
title A Generalized Fréchet Test for Object Data with Unequal Repeated Measurements
topic Methodology
url https://arxiv.org/abs/2503.01514