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Main Authors: Liu, Xiangrui, Zhang, Yuanyuan, Shang, Qianyu, Lu, Yingzhou, Yin, Changchang, Hu, Xiaoling, Liu, Xiaoou, Chen, Lulu, Rodríguez, Alexander, Yang, Yezhou, Zhang, Ping, Chen, Jintai, Du, Shan, Yao, Huaxiu, Wang, Sheng, Fu, Tianfan, Wang, Xiao
Format: Preprint
Published: 2025
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Online Access:https://arxiv.org/abs/2503.02104
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author Liu, Xiangrui
Zhang, Yuanyuan
Shang, Qianyu
Lu, Yingzhou
Yin, Changchang
Hu, Xiaoling
Liu, Xiaoou
Chen, Lulu
Rodríguez, Alexander
Yang, Yezhou
Zhang, Ping
Chen, Jintai
Du, Shan
Yao, Huaxiu
Wang, Sheng
Fu, Tianfan
Wang, Xiao
author_facet Liu, Xiangrui
Zhang, Yuanyuan
Shang, Qianyu
Lu, Yingzhou
Yin, Changchang
Hu, Xiaoling
Liu, Xiaoou
Chen, Lulu
Rodríguez, Alexander
Yang, Yezhou
Zhang, Ping
Chen, Jintai
Du, Shan
Yao, Huaxiu
Wang, Sheng
Fu, Tianfan
Wang, Xiao
contents Foundation models, first introduced in 2021, refer to large-scale pretrained models (e.g., large language models (LLMs) and vision-language models (VLMs)) that learn from extensive unlabeled datasets through unsupervised methods, enabling them to excel in diverse downstream tasks. These models, like GPT, can be adapted to various applications such as question answering and visual understanding, outperforming task-specific AI models and earning their name due to broad applicability across fields. The development of biomedical foundation models marks a significant milestone in the use of artificial intelligence (AI) to understand complex biological phenomena and advance medical research and practice. This survey explores the potential of foundation models in diverse domains within biomedical fields, including computational biology, drug discovery and development, clinical informatics, medical imaging, and public health. The purpose of this survey is to inspire ongoing research in the application of foundation models to health science.
format Preprint
id arxiv_https___arxiv_org_abs_2503_02104
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Foundation Model in Biomedicine
Liu, Xiangrui
Zhang, Yuanyuan
Shang, Qianyu
Lu, Yingzhou
Yin, Changchang
Hu, Xiaoling
Liu, Xiaoou
Chen, Lulu
Rodríguez, Alexander
Yang, Yezhou
Zhang, Ping
Chen, Jintai
Du, Shan
Yao, Huaxiu
Wang, Sheng
Fu, Tianfan
Wang, Xiao
Machine Learning
Artificial Intelligence
Foundation models, first introduced in 2021, refer to large-scale pretrained models (e.g., large language models (LLMs) and vision-language models (VLMs)) that learn from extensive unlabeled datasets through unsupervised methods, enabling them to excel in diverse downstream tasks. These models, like GPT, can be adapted to various applications such as question answering and visual understanding, outperforming task-specific AI models and earning their name due to broad applicability across fields. The development of biomedical foundation models marks a significant milestone in the use of artificial intelligence (AI) to understand complex biological phenomena and advance medical research and practice. This survey explores the potential of foundation models in diverse domains within biomedical fields, including computational biology, drug discovery and development, clinical informatics, medical imaging, and public health. The purpose of this survey is to inspire ongoing research in the application of foundation models to health science.
title Foundation Model in Biomedicine
topic Machine Learning
Artificial Intelligence
url https://arxiv.org/abs/2503.02104