GBT-SAM: A Parameter-Efficient Depth-Aware Model for Generalizable Brain tumour Segmentation on mp-MRI

Fuente: arXiv
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Main Authors: Diana-Albelda, Cecilia, Alcover-Couso, Roberto, García-Martín, Álvaro, Bescos, Jesus, Escudero-Viñolo, Marcos
Format: Preprint
Published: 2025
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author Diana-Albelda, Cecilia
Alcover-Couso, Roberto
García-Martín, Álvaro
Bescos, Jesus
Escudero-Viñolo, Marcos
author_facet Diana-Albelda, Cecilia
Alcover-Couso, Roberto
García-Martín, Álvaro
Bescos, Jesus
Escudero-Viñolo, Marcos
contents Gliomas are aggressive brain tumors that require accurate imaging-based diagnosis, with segmentation playing a critical role in evaluating morphology and treatment decisions. Manual delineation of gliomas is time-consuming and prone to variability, motivating the use of deep learning to improve consistency and alleviate clinical workload. However, existing methods often fail to fully exploit the information available in multi-parametric MRI (mp-MRI), particularly inter-slice contextual features, and typically require considerable computational resources while lacking robustness across tumor type variations. We present GBT-SAM, a parameter-efficient deep learning framework that adapts the Segment Anything Model (SAM), a large-scale vision model, to volumetric mp-MRI data. GBT-SAM reduces input complexity by selecting fewer than 2.6\% of slices per scan while incorporating all four MRI modalities, preserving essential tumor-related information with minimal cost. Furthermore, our model is trained by a two-step fine-tuning strategy that incorporates a depth-aware module to capture inter-slice correlations and lightweight adaptation layers, resulting in just 6.5M trainable parameters, which is the lowest among SAM-based approaches. GBT-SAM achieves a Dice Score of 93.54 on the BraTS Adult Glioma dataset and demonstrates robust performance on Meningioma, Pediatric Glioma, and Sub-Saharan Glioma datasets. These results highlight GBT-SAM's potential as a computationally efficient and domain-robust framework for brain tumor segmentation using mp-MRI. Our code and models are available at https://github.com/vpulab/med-sam-brain .
format Preprint
id arxiv_https___arxiv_org_abs_2503_04325
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle GBT-SAM: A Parameter-Efficient Depth-Aware Model for Generalizable Brain tumour Segmentation on mp-MRI
Diana-Albelda, Cecilia
Alcover-Couso, Roberto
García-Martín, Álvaro
Bescos, Jesus
Escudero-Viñolo, Marcos
Image and Video Processing
Computer Vision and Pattern Recognition
Gliomas are aggressive brain tumors that require accurate imaging-based diagnosis, with segmentation playing a critical role in evaluating morphology and treatment decisions. Manual delineation of gliomas is time-consuming and prone to variability, motivating the use of deep learning to improve consistency and alleviate clinical workload. However, existing methods often fail to fully exploit the information available in multi-parametric MRI (mp-MRI), particularly inter-slice contextual features, and typically require considerable computational resources while lacking robustness across tumor type variations. We present GBT-SAM, a parameter-efficient deep learning framework that adapts the Segment Anything Model (SAM), a large-scale vision model, to volumetric mp-MRI data. GBT-SAM reduces input complexity by selecting fewer than 2.6\% of slices per scan while incorporating all four MRI modalities, preserving essential tumor-related information with minimal cost. Furthermore, our model is trained by a two-step fine-tuning strategy that incorporates a depth-aware module to capture inter-slice correlations and lightweight adaptation layers, resulting in just 6.5M trainable parameters, which is the lowest among SAM-based approaches. GBT-SAM achieves a Dice Score of 93.54 on the BraTS Adult Glioma dataset and demonstrates robust performance on Meningioma, Pediatric Glioma, and Sub-Saharan Glioma datasets. These results highlight GBT-SAM's potential as a computationally efficient and domain-robust framework for brain tumor segmentation using mp-MRI. Our code and models are available at https://github.com/vpulab/med-sam-brain .
title GBT-SAM: A Parameter-Efficient Depth-Aware Model for Generalizable Brain tumour Segmentation on mp-MRI
topic Image and Video Processing
Computer Vision and Pattern Recognition
url https://arxiv.org/abs/2503.04325