Enhancing SAM with Efficient Prompting and Preference Optimization for Semi-supervised Medical Image Segmentation

Fuente: arXiv
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Main Authors: Konwer, Aishik, Yang, Zhijian, Bas, Erhan, Xiao, Cao, Prasanna, Prateek, Bhatia, Parminder, Kass-Hout, Taha
Format: Preprint
Published: 2025
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author Konwer, Aishik
Yang, Zhijian
Bas, Erhan
Xiao, Cao
Prasanna, Prateek
Bhatia, Parminder
Kass-Hout, Taha
author_facet Konwer, Aishik
Yang, Zhijian
Bas, Erhan
Xiao, Cao
Prasanna, Prateek
Bhatia, Parminder
Kass-Hout, Taha
contents Foundational models such as the Segment Anything Model (SAM) are gaining traction in medical imaging segmentation, supporting multiple downstream tasks. However, such models are supervised in nature, still relying on large annotated datasets or prompts supplied by experts. Conventional techniques such as active learning to alleviate such limitations are limited in scope and still necessitate continuous human involvement and complex domain knowledge for label refinement or establishing reward ground truth. To address these challenges, we propose an enhanced Segment Anything Model (SAM) framework that utilizes annotation-efficient prompts generated in a fully unsupervised fashion, while still capturing essential semantic, location, and shape information through contrastive language-image pretraining and visual question answering. We adopt the direct preference optimization technique to design an optimal policy that enables the model to generate high-fidelity segmentations with simple ratings or rankings provided by a virtual annotator simulating the human annotation process. State-of-the-art performance of our framework in tasks such as lung segmentation, breast tumor segmentation, and organ segmentation across various modalities, including X-ray, ultrasound, and abdominal CT, justifies its effectiveness in low-annotation data scenarios.
format Preprint
id arxiv_https___arxiv_org_abs_2503_04639
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Enhancing SAM with Efficient Prompting and Preference Optimization for Semi-supervised Medical Image Segmentation
Konwer, Aishik
Yang, Zhijian
Bas, Erhan
Xiao, Cao
Prasanna, Prateek
Bhatia, Parminder
Kass-Hout, Taha
Computer Vision and Pattern Recognition
Machine Learning
Foundational models such as the Segment Anything Model (SAM) are gaining traction in medical imaging segmentation, supporting multiple downstream tasks. However, such models are supervised in nature, still relying on large annotated datasets or prompts supplied by experts. Conventional techniques such as active learning to alleviate such limitations are limited in scope and still necessitate continuous human involvement and complex domain knowledge for label refinement or establishing reward ground truth. To address these challenges, we propose an enhanced Segment Anything Model (SAM) framework that utilizes annotation-efficient prompts generated in a fully unsupervised fashion, while still capturing essential semantic, location, and shape information through contrastive language-image pretraining and visual question answering. We adopt the direct preference optimization technique to design an optimal policy that enables the model to generate high-fidelity segmentations with simple ratings or rankings provided by a virtual annotator simulating the human annotation process. State-of-the-art performance of our framework in tasks such as lung segmentation, breast tumor segmentation, and organ segmentation across various modalities, including X-ray, ultrasound, and abdominal CT, justifies its effectiveness in low-annotation data scenarios.
title Enhancing SAM with Efficient Prompting and Preference Optimization for Semi-supervised Medical Image Segmentation
topic Computer Vision and Pattern Recognition
Machine Learning
url https://arxiv.org/abs/2503.04639