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Main Authors: Valverde, Juan Miguel, Østergaard, Maja, Rodriguez-Palomo, Adrian, Vibe, Peter Alling Strange, Wittig, Nina Kølln, Birkedal, Henrik, Dahl, Anders Bjorholm
Format: Preprint
Published: 2025
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Online Access:https://arxiv.org/abs/2503.05541
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author Valverde, Juan Miguel
Østergaard, Maja
Rodriguez-Palomo, Adrian
Vibe, Peter Alling Strange
Wittig, Nina Kølln
Birkedal, Henrik
Dahl, Anders Bjorholm
author_facet Valverde, Juan Miguel
Østergaard, Maja
Rodriguez-Palomo, Adrian
Vibe, Peter Alling Strange
Wittig, Nina Kølln
Birkedal, Henrik
Dahl, Anders Bjorholm
contents Accurate segmentation of thin, tubular structures (e.g., blood vessels) is challenging for deep neural networks. These networks classify individual pixels, and even minor misclassifications can break the thin connections within these structures. Existing methods for improving topology accuracy, such as topology loss functions, rely on very precise, topologically-accurate training labels, which are difficult to obtain. This is because annotating images, especially 3D images, is extremely laborious and time-consuming. Low image resolution and contrast further complicates the annotation by causing tubular structures to appear disconnected. We present CoLeTra, a data augmentation strategy that integrates to the models the prior knowledge that structures that appear broken are actually connected. This is achieved by creating images with the appearance of disconnected structures while maintaining the original labels. Our extensive experiments, involving different architectures, loss functions, and datasets, demonstrate that CoLeTra leads to segmentations topologically more accurate while often improving the Dice coefficient and Hausdorff distance. CoLeTra's hyper-parameters are intuitive to tune, and our sensitivity analysis shows that CoLeTra is robust to changes in these hyper-parameters. We also release a dataset specifically suited for image segmentation methods with a focus on topology accuracy. CoLetra's code can be found at https://github.com/jmlipman/CoLeTra.
format Preprint
id arxiv_https___arxiv_org_abs_2503_05541
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Disconnect to Connect: A Data Augmentation Method for Improving Topology Accuracy in Image Segmentation
Valverde, Juan Miguel
Østergaard, Maja
Rodriguez-Palomo, Adrian
Vibe, Peter Alling Strange
Wittig, Nina Kølln
Birkedal, Henrik
Dahl, Anders Bjorholm
Computer Vision and Pattern Recognition
Accurate segmentation of thin, tubular structures (e.g., blood vessels) is challenging for deep neural networks. These networks classify individual pixels, and even minor misclassifications can break the thin connections within these structures. Existing methods for improving topology accuracy, such as topology loss functions, rely on very precise, topologically-accurate training labels, which are difficult to obtain. This is because annotating images, especially 3D images, is extremely laborious and time-consuming. Low image resolution and contrast further complicates the annotation by causing tubular structures to appear disconnected. We present CoLeTra, a data augmentation strategy that integrates to the models the prior knowledge that structures that appear broken are actually connected. This is achieved by creating images with the appearance of disconnected structures while maintaining the original labels. Our extensive experiments, involving different architectures, loss functions, and datasets, demonstrate that CoLeTra leads to segmentations topologically more accurate while often improving the Dice coefficient and Hausdorff distance. CoLeTra's hyper-parameters are intuitive to tune, and our sensitivity analysis shows that CoLeTra is robust to changes in these hyper-parameters. We also release a dataset specifically suited for image segmentation methods with a focus on topology accuracy. CoLetra's code can be found at https://github.com/jmlipman/CoLeTra.
title Disconnect to Connect: A Data Augmentation Method for Improving Topology Accuracy in Image Segmentation
topic Computer Vision and Pattern Recognition
url https://arxiv.org/abs/2503.05541