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Auteurs principaux: Zenati, Houssam, Abécassis, Judith, Josse, Julie, Thirion, Bertrand
Format: Preprint
Publié: 2025
Sujets:
Accès en ligne:https://arxiv.org/abs/2503.06156
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author Zenati, Houssam
Abécassis, Judith
Josse, Julie
Thirion, Bertrand
author_facet Zenati, Houssam
Abécassis, Judith
Josse, Julie
Thirion, Bertrand
contents Uncovering causal mediation effects is of significant value to practitioners seeking to isolate the direct treatment effect from the potential mediated effect. We propose a double machine learning (DML) algorithm for mediation analysis that supports continuous treatments. To estimate the target mediated response curve, our method uses a kernel-based doubly robust moment function for which we prove asymptotic Neyman orthogonality. This allows us to obtain asymptotic normality with nonparametric convergence rate while allowing for nonparametric or parametric estimation of the nuisance parameters. We then derive an optimal bandwidth strategy along with a procedure for estimating asymptotic confidence intervals. Finally, to illustrate the benefits of our method, we provide a numerical evaluation of our approach on a simulation along with an application to real-world medical data to analyze the effect of glycemic control on cognitive functions.
format Preprint
id arxiv_https___arxiv_org_abs_2503_06156
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Double Debiased Machine Learning for Mediation Analysis with Continuous Treatments
Zenati, Houssam
Abécassis, Judith
Josse, Julie
Thirion, Bertrand
Machine Learning
Uncovering causal mediation effects is of significant value to practitioners seeking to isolate the direct treatment effect from the potential mediated effect. We propose a double machine learning (DML) algorithm for mediation analysis that supports continuous treatments. To estimate the target mediated response curve, our method uses a kernel-based doubly robust moment function for which we prove asymptotic Neyman orthogonality. This allows us to obtain asymptotic normality with nonparametric convergence rate while allowing for nonparametric or parametric estimation of the nuisance parameters. We then derive an optimal bandwidth strategy along with a procedure for estimating asymptotic confidence intervals. Finally, to illustrate the benefits of our method, we provide a numerical evaluation of our approach on a simulation along with an application to real-world medical data to analyze the effect of glycemic control on cognitive functions.
title Double Debiased Machine Learning for Mediation Analysis with Continuous Treatments
topic Machine Learning
url https://arxiv.org/abs/2503.06156