From $\mathcal{O}(n^{2})$ to $\mathcal{O}(n)$ Parameters: Quantum Self-Attention in Vision Transformers for Biomedical Image Classification

Fuente: arXiv
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Autori principali: Boucher, Thomas, Whittle, John, Mazomenos, Evangelos B.
Natura: Preprint
Pubblicazione: 2025
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author Boucher, Thomas
Whittle, John
Mazomenos, Evangelos B.
author_facet Boucher, Thomas
Whittle, John
Mazomenos, Evangelos B.
contents We demonstrate that quantum vision transformers (QViTs), vision transformers (ViTs) with self-attention (SA) mechanisms replaced by quantum self-attention (QSA) mechanisms, can match state-of-the-art (SOTA) biomedical image classifiers while using 99.99% fewer parameters. QSAs are produced by replacing linear SA layers with parameterised quantum neural networks (QNNs), producing a QSA mechanism and reducing parameter scaling from $\mathcal{O}(n^2)$ to $\mathcal{O}(n)$. On RetinaMNIST, our ultra parameter-efficient QViT outperforms 13/14 SOTA methods including CNNs and ViTs, achieving 56.5% accuracy, just 0.88% below the top MedMamba model while using 99.99% fewer parameters (1K vs 14.5M) and 89% fewer GFLOPs. We present the first investigation of knowledge distillation (KD) from classical to quantum vision transformers in biomedical image classification, showing that QViTs maintain comparable performance to classical ViTs across eight diverse datasets spanning multiple modalities, with improved QSA parameter-efficiency. Our higher-qubit architecture benefitted more from KD pre-training, suggesting a scaling relationship between QSA parameters and KD effectiveness. These findings establish QSA as a practical architectural choice toward parameter-efficient biomedical image analysis.
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id arxiv_https___arxiv_org_abs_2503_07294
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle From $\mathcal{O}(n^{2})$ to $\mathcal{O}(n)$ Parameters: Quantum Self-Attention in Vision Transformers for Biomedical Image Classification
Boucher, Thomas
Whittle, John
Mazomenos, Evangelos B.
Computer Vision and Pattern Recognition
Artificial Intelligence
Machine Learning
We demonstrate that quantum vision transformers (QViTs), vision transformers (ViTs) with self-attention (SA) mechanisms replaced by quantum self-attention (QSA) mechanisms, can match state-of-the-art (SOTA) biomedical image classifiers while using 99.99% fewer parameters. QSAs are produced by replacing linear SA layers with parameterised quantum neural networks (QNNs), producing a QSA mechanism and reducing parameter scaling from $\mathcal{O}(n^2)$ to $\mathcal{O}(n)$. On RetinaMNIST, our ultra parameter-efficient QViT outperforms 13/14 SOTA methods including CNNs and ViTs, achieving 56.5% accuracy, just 0.88% below the top MedMamba model while using 99.99% fewer parameters (1K vs 14.5M) and 89% fewer GFLOPs. We present the first investigation of knowledge distillation (KD) from classical to quantum vision transformers in biomedical image classification, showing that QViTs maintain comparable performance to classical ViTs across eight diverse datasets spanning multiple modalities, with improved QSA parameter-efficiency. Our higher-qubit architecture benefitted more from KD pre-training, suggesting a scaling relationship between QSA parameters and KD effectiveness. These findings establish QSA as a practical architectural choice toward parameter-efficient biomedical image analysis.
title From $\mathcal{O}(n^{2})$ to $\mathcal{O}(n)$ Parameters: Quantum Self-Attention in Vision Transformers for Biomedical Image Classification
topic Computer Vision and Pattern Recognition
Artificial Intelligence
Machine Learning
url https://arxiv.org/abs/2503.07294