LLaVA-RadZ: Can Multimodal Large Language Models Effectively Tackle Zero-shot Radiology Recognition?

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Hauptverfasser: Li, Bangyan, Huang, Wenxuan, Gao, Zhenkun, Wang, Yeqiang, Shen, Yunhang, Lin, Jingzhong, You, Ling, Shen, Yuxiang, Lin, Shaohui, Ouyang, Wanli, Sun, Yuling
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Veröffentlicht: 2025
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author Li, Bangyan
Huang, Wenxuan
Gao, Zhenkun
Wang, Yeqiang
Shen, Yunhang
Lin, Jingzhong
You, Ling
Shen, Yuxiang
Lin, Shaohui
Ouyang, Wanli
Sun, Yuling
author_facet Li, Bangyan
Huang, Wenxuan
Gao, Zhenkun
Wang, Yeqiang
Shen, Yunhang
Lin, Jingzhong
You, Ling
Shen, Yuxiang
Lin, Shaohui
Ouyang, Wanli
Sun, Yuling
contents Recently, Multimodal Large Language Models (MLLMs) have demonstrated exceptional capabilities in visual understanding and reasoning across various vision-language tasks. However, we found that MLLMs cannot process effectively from fine-grained medical image data in the traditional Visual Question Answering (VQA) pipeline, as they do not exploit the captured features and available medical knowledge fully, results in MLLMs usually performing poorly in zero-shot medical disease recognition. Fortunately, this limitation does not indicate that MLLMs are fundamentally incapable of addressing fine-grained recognition tasks. From a feature representation perspective, MLLMs demonstrate considerable potential for tackling such challenging problems. Thus, to address this challenge, we propose LLaVA-RadZ, a simple yet effective framework for zero-shot medical disease recognition via utilizing the existing MLLM features. Specifically, we design an end-to-end training strategy, termed Decoding-Side Feature Alignment Training (DFAT) to take advantage of the characteristics of the MLLM decoder architecture and incorporate modality-specific tokens tailored for different modalities. Additionally, we introduce a Domain Knowledge Anchoring Module (DKAM) to exploit the intrinsic medical knowledge of large models, which mitigates the category semantic gap in image-text alignment. Extensive experiments demonstrate that our LLaVA-RadZ significantly outperforms traditional MLLMs in zero-shot disease recognition, achieving the comparable performance to the well-established and highly-optimized CLIP-based approaches.
format Preprint
id arxiv_https___arxiv_org_abs_2503_07487
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle LLaVA-RadZ: Can Multimodal Large Language Models Effectively Tackle Zero-shot Radiology Recognition?
Li, Bangyan
Huang, Wenxuan
Gao, Zhenkun
Wang, Yeqiang
Shen, Yunhang
Lin, Jingzhong
You, Ling
Shen, Yuxiang
Lin, Shaohui
Ouyang, Wanli
Sun, Yuling
Computer Vision and Pattern Recognition
Recently, Multimodal Large Language Models (MLLMs) have demonstrated exceptional capabilities in visual understanding and reasoning across various vision-language tasks. However, we found that MLLMs cannot process effectively from fine-grained medical image data in the traditional Visual Question Answering (VQA) pipeline, as they do not exploit the captured features and available medical knowledge fully, results in MLLMs usually performing poorly in zero-shot medical disease recognition. Fortunately, this limitation does not indicate that MLLMs are fundamentally incapable of addressing fine-grained recognition tasks. From a feature representation perspective, MLLMs demonstrate considerable potential for tackling such challenging problems. Thus, to address this challenge, we propose LLaVA-RadZ, a simple yet effective framework for zero-shot medical disease recognition via utilizing the existing MLLM features. Specifically, we design an end-to-end training strategy, termed Decoding-Side Feature Alignment Training (DFAT) to take advantage of the characteristics of the MLLM decoder architecture and incorporate modality-specific tokens tailored for different modalities. Additionally, we introduce a Domain Knowledge Anchoring Module (DKAM) to exploit the intrinsic medical knowledge of large models, which mitigates the category semantic gap in image-text alignment. Extensive experiments demonstrate that our LLaVA-RadZ significantly outperforms traditional MLLMs in zero-shot disease recognition, achieving the comparable performance to the well-established and highly-optimized CLIP-based approaches.
title LLaVA-RadZ: Can Multimodal Large Language Models Effectively Tackle Zero-shot Radiology Recognition?
topic Computer Vision and Pattern Recognition
url https://arxiv.org/abs/2503.07487