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Bibliographic Details
Main Authors: Aurouet, Daphné, Patilea, Valentin
Format: Preprint
Published: 2025
Subjects:
Online Access:https://arxiv.org/abs/2503.08356
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author Aurouet, Daphné
Patilea, Valentin
author_facet Aurouet, Daphné
Patilea, Valentin
contents Motivated by the need to analyze continuously updated data sets in the context of time-to-event modeling, we propose a novel nonparametric approach to estimate the conditional hazard function given a set of continuous and discrete predictors. The method is based on a representation of the conditional hazard as a ratio between a joint density and a conditional expectation determined by the distribution of the observed variables. It is shown that such ratio representations are available for uni- and bivariate time-to-events, in the presence of common types of random censoring, truncation, and with possibly cured individuals, as well as for competing risks. This opens the door to nonparametric approaches in many time-to-event predictive models. To estimate joint densities and conditional expectations we propose the recursive kernel smoothing, which is well suited for online estimation. Asymptotic results for such estimators are derived and it is shown that they achieve optimal convergence rates. Simulation experiments show the good finite sample performance of our recursive estimator with right censoring. The method is applied to a real dataset of primary breast cancer.
format Preprint
id arxiv_https___arxiv_org_abs_2503_08356
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Continuously updated estimation of conditional hazard functions
Aurouet, Daphné
Patilea, Valentin
Methodology
Motivated by the need to analyze continuously updated data sets in the context of time-to-event modeling, we propose a novel nonparametric approach to estimate the conditional hazard function given a set of continuous and discrete predictors. The method is based on a representation of the conditional hazard as a ratio between a joint density and a conditional expectation determined by the distribution of the observed variables. It is shown that such ratio representations are available for uni- and bivariate time-to-events, in the presence of common types of random censoring, truncation, and with possibly cured individuals, as well as for competing risks. This opens the door to nonparametric approaches in many time-to-event predictive models. To estimate joint densities and conditional expectations we propose the recursive kernel smoothing, which is well suited for online estimation. Asymptotic results for such estimators are derived and it is shown that they achieve optimal convergence rates. Simulation experiments show the good finite sample performance of our recursive estimator with right censoring. The method is applied to a real dataset of primary breast cancer.
title Continuously updated estimation of conditional hazard functions
topic Methodology
url https://arxiv.org/abs/2503.08356