SeqSAM: Autoregressive Multiple Hypothesis Prediction for Medical Image Segmentation using SAM

Fuente: arXiv
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Auteurs principaux: Towle, Benjamin, Chen, Xin, Zhou, Ke
Format: Preprint
Publié: 2025
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author Towle, Benjamin
Chen, Xin
Zhou, Ke
author_facet Towle, Benjamin
Chen, Xin
Zhou, Ke
contents Pre-trained segmentation models are a powerful and flexible tool for segmenting images. Recently, this trend has extended to medical imaging. Yet, often these methods only produce a single prediction for a given image, neglecting inherent uncertainty in medical images, due to unclear object boundaries and errors caused by the annotation tool. Multiple Choice Learning is a technique for generating multiple masks, through multiple learned prediction heads. However, this cannot readily be extended to producing more outputs than its initial pre-training hyperparameters, as the sparse, winner-takes-all loss function makes it easy for one prediction head to become overly dominant, thus not guaranteeing the clinical relevancy of each mask produced. We introduce SeqSAM, a sequential, RNN-inspired approach to generating multiple masks, which uses a bipartite matching loss for ensuring the clinical relevancy of each mask, and can produce an arbitrary number of masks. We show notable improvements in quality of each mask produced across two publicly available datasets. Our code is available at https://github.com/BenjaminTowle/SeqSAM.
format Preprint
id arxiv_https___arxiv_org_abs_2503_09797
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle SeqSAM: Autoregressive Multiple Hypothesis Prediction for Medical Image Segmentation using SAM
Towle, Benjamin
Chen, Xin
Zhou, Ke
Computer Vision and Pattern Recognition
Artificial Intelligence
Machine Learning
Pre-trained segmentation models are a powerful and flexible tool for segmenting images. Recently, this trend has extended to medical imaging. Yet, often these methods only produce a single prediction for a given image, neglecting inherent uncertainty in medical images, due to unclear object boundaries and errors caused by the annotation tool. Multiple Choice Learning is a technique for generating multiple masks, through multiple learned prediction heads. However, this cannot readily be extended to producing more outputs than its initial pre-training hyperparameters, as the sparse, winner-takes-all loss function makes it easy for one prediction head to become overly dominant, thus not guaranteeing the clinical relevancy of each mask produced. We introduce SeqSAM, a sequential, RNN-inspired approach to generating multiple masks, which uses a bipartite matching loss for ensuring the clinical relevancy of each mask, and can produce an arbitrary number of masks. We show notable improvements in quality of each mask produced across two publicly available datasets. Our code is available at https://github.com/BenjaminTowle/SeqSAM.
title SeqSAM: Autoregressive Multiple Hypothesis Prediction for Medical Image Segmentation using SAM
topic Computer Vision and Pattern Recognition
Artificial Intelligence
Machine Learning
url https://arxiv.org/abs/2503.09797