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Main Authors: Lian, Wenyi, Micke, Patrick, Lindblad, Joakim, Sladoje, Nataša
Format: Preprint
Published: 2025
Subjects:
Online Access:https://arxiv.org/abs/2503.09826
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author Lian, Wenyi
Micke, Patrick
Lindblad, Joakim
Sladoje, Nataša
author_facet Lian, Wenyi
Micke, Patrick
Lindblad, Joakim
Sladoje, Nataša
contents Vision Transformers (ViTs) have achieved remarkable success in standard RGB image processing tasks. However, applying ViTs to multi-channel imaging (MCI) data, e.g., for medical and remote sensing applications, remains a challenge. In particular, MCI data often consist of layers acquired from different modalities. Directly training ViTs on such data can obscure complementary information and impair the performance. In this paper, we introduce a simple yet effective pretraining framework for large-scale MCI datasets. Our method, named Isolated Channel ViT (IC-ViT), patchifies image channels individually and thereby enables pretraining for multimodal multi-channel tasks. We show that this channel-wise patchifying is a key technique for MCI processing. More importantly, one can pretrain the IC-ViT on single channels and finetune it on downstream multi-channel datasets. This pretraining framework captures dependencies between patches as well as channels and produces robust feature representation. Experiments on various tasks and benchmarks, including JUMP-CP and CHAMMI for cell microscopy imaging, and So2Sat-LCZ42 for satellite imaging, show that the proposed IC-ViT delivers 4-14 percentage points of performance improvement over existing channel-adaptive approaches. Further, its efficient training makes it a suitable candidate for large-scale pretraining of foundation models on heterogeneous data. Our code is available at https://github.com/shermanlian/IC-ViT.
format Preprint
id arxiv_https___arxiv_org_abs_2503_09826
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Isolated Channel Vision Transformers: From Single-Channel Pretraining to Multi-Channel Finetuning
Lian, Wenyi
Micke, Patrick
Lindblad, Joakim
Sladoje, Nataša
Computer Vision and Pattern Recognition
Vision Transformers (ViTs) have achieved remarkable success in standard RGB image processing tasks. However, applying ViTs to multi-channel imaging (MCI) data, e.g., for medical and remote sensing applications, remains a challenge. In particular, MCI data often consist of layers acquired from different modalities. Directly training ViTs on such data can obscure complementary information and impair the performance. In this paper, we introduce a simple yet effective pretraining framework for large-scale MCI datasets. Our method, named Isolated Channel ViT (IC-ViT), patchifies image channels individually and thereby enables pretraining for multimodal multi-channel tasks. We show that this channel-wise patchifying is a key technique for MCI processing. More importantly, one can pretrain the IC-ViT on single channels and finetune it on downstream multi-channel datasets. This pretraining framework captures dependencies between patches as well as channels and produces robust feature representation. Experiments on various tasks and benchmarks, including JUMP-CP and CHAMMI for cell microscopy imaging, and So2Sat-LCZ42 for satellite imaging, show that the proposed IC-ViT delivers 4-14 percentage points of performance improvement over existing channel-adaptive approaches. Further, its efficient training makes it a suitable candidate for large-scale pretraining of foundation models on heterogeneous data. Our code is available at https://github.com/shermanlian/IC-ViT.
title Isolated Channel Vision Transformers: From Single-Channel Pretraining to Multi-Channel Finetuning
topic Computer Vision and Pattern Recognition
url https://arxiv.org/abs/2503.09826