CountPath: Automating Fragment Counting in Digital Pathology

Fuente: arXiv
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Main Authors: Vieira, Ana Beatriz, Valente, Maria, Montezuma, Diana, Albuquerque, Tomé, Ribeiro, Liliana, Oliveira, Domingos, Monteiro, João, Gonçalves, Sofia, Pinto, Isabel M., Cardoso, Jaime S., Oliveira, Arlindo L.
Format: Preprint
Published: 2025
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author Vieira, Ana Beatriz
Valente, Maria
Montezuma, Diana
Albuquerque, Tomé
Ribeiro, Liliana
Oliveira, Domingos
Monteiro, João
Gonçalves, Sofia
Pinto, Isabel M.
Cardoso, Jaime S.
Oliveira, Arlindo L.
author_facet Vieira, Ana Beatriz
Valente, Maria
Montezuma, Diana
Albuquerque, Tomé
Ribeiro, Liliana
Oliveira, Domingos
Monteiro, João
Gonçalves, Sofia
Pinto, Isabel M.
Cardoso, Jaime S.
Oliveira, Arlindo L.
contents Quality control of medical images is a critical component of digital pathology, ensuring that diagnostic images meet required standards. A pre-analytical task within this process is the verification of the number of specimen fragments, a process that ensures that the number of fragments on a slide matches the number documented in the macroscopic report. This step is important to ensure that the slides contain the appropriate diagnostic material from the grossing process, thereby guaranteeing the accuracy of subsequent microscopic examination and diagnosis. Traditionally, this assessment is performed manually, requiring significant time and effort while being subject to significant variability due to its subjective nature. To address these challenges, this study explores an automated approach to fragment counting using the YOLOv9 and Vision Transformer models. Our results demonstrate that the automated system achieves a level of performance comparable to expert assessments, offering a reliable and efficient alternative to manual counting. Additionally, we present findings on interobserver variability, showing that the automated approach achieves an accuracy of 86%, which falls within the range of variation observed among experts (82-88%), further supporting its potential for integration into routine pathology workflows.
format Preprint
id arxiv_https___arxiv_org_abs_2503_10520
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle CountPath: Automating Fragment Counting in Digital Pathology
Vieira, Ana Beatriz
Valente, Maria
Montezuma, Diana
Albuquerque, Tomé
Ribeiro, Liliana
Oliveira, Domingos
Monteiro, João
Gonçalves, Sofia
Pinto, Isabel M.
Cardoso, Jaime S.
Oliveira, Arlindo L.
Computer Vision and Pattern Recognition
Artificial Intelligence
Machine Learning
I.2; I.4
Quality control of medical images is a critical component of digital pathology, ensuring that diagnostic images meet required standards. A pre-analytical task within this process is the verification of the number of specimen fragments, a process that ensures that the number of fragments on a slide matches the number documented in the macroscopic report. This step is important to ensure that the slides contain the appropriate diagnostic material from the grossing process, thereby guaranteeing the accuracy of subsequent microscopic examination and diagnosis. Traditionally, this assessment is performed manually, requiring significant time and effort while being subject to significant variability due to its subjective nature. To address these challenges, this study explores an automated approach to fragment counting using the YOLOv9 and Vision Transformer models. Our results demonstrate that the automated system achieves a level of performance comparable to expert assessments, offering a reliable and efficient alternative to manual counting. Additionally, we present findings on interobserver variability, showing that the automated approach achieves an accuracy of 86%, which falls within the range of variation observed among experts (82-88%), further supporting its potential for integration into routine pathology workflows.
title CountPath: Automating Fragment Counting in Digital Pathology
topic Computer Vision and Pattern Recognition
Artificial Intelligence
Machine Learning
I.2; I.4
url https://arxiv.org/abs/2503.10520