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Auteurs principaux: Wang, Zhifeng, Yi, Renjiao, Wen, Xin, Zhu, Chenyang, Xu, Kai
Format: Preprint
Publié: 2025
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Accès en ligne:https://arxiv.org/abs/2503.12758
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author Wang, Zhifeng
Yi, Renjiao
Wen, Xin
Zhu, Chenyang
Xu, Kai
author_facet Wang, Zhifeng
Yi, Renjiao
Wen, Xin
Zhu, Chenyang
Xu, Kai
contents Angiography imaging is a medical imaging technique that enhances the visibility of blood vessels within the body by using contrast agents. Angiographic images can effectively assist in the diagnosis of vascular diseases. However, contrast agents may bring extra radiation exposure which is harmful to patients with health risks. To mitigate these concerns, in this paper, we aim to automatically generate angiography from non-angiographic inputs, by leveraging and enhancing the inherent physical properties of vascular structures. Previous methods relying on 2D slice-based angiography synthesis struggle with maintaining continuity in 3D vascular structures and exhibit limited effectiveness across different imaging modalities. We propose VasTSD, a 3D vascular tree-state space diffusion model to synthesize angiography from 3D non-angiographic volumes, with a novel state space serialization approach that dynamically constructs vascular tree topologies, integrating these with a diffusion-based generative model to ensure the generation of anatomically continuous vasculature in 3D volumes. A pre-trained vision embedder is employed to construct vascular state space representations, enabling consistent modeling of vascular structures across multiple modalities. Extensive experiments on various angiographic datasets demonstrate the superiority of VasTSD over prior works, achieving enhanced continuity of blood vessels in synthesized angiographic synthesis for multiple modalities and anatomical regions.
format Preprint
id arxiv_https___arxiv_org_abs_2503_12758
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle VasTSD: Learning 3D Vascular Tree-state Space Diffusion Model for Angiography Synthesis
Wang, Zhifeng
Yi, Renjiao
Wen, Xin
Zhu, Chenyang
Xu, Kai
Computer Vision and Pattern Recognition
Image and Video Processing
Angiography imaging is a medical imaging technique that enhances the visibility of blood vessels within the body by using contrast agents. Angiographic images can effectively assist in the diagnosis of vascular diseases. However, contrast agents may bring extra radiation exposure which is harmful to patients with health risks. To mitigate these concerns, in this paper, we aim to automatically generate angiography from non-angiographic inputs, by leveraging and enhancing the inherent physical properties of vascular structures. Previous methods relying on 2D slice-based angiography synthesis struggle with maintaining continuity in 3D vascular structures and exhibit limited effectiveness across different imaging modalities. We propose VasTSD, a 3D vascular tree-state space diffusion model to synthesize angiography from 3D non-angiographic volumes, with a novel state space serialization approach that dynamically constructs vascular tree topologies, integrating these with a diffusion-based generative model to ensure the generation of anatomically continuous vasculature in 3D volumes. A pre-trained vision embedder is employed to construct vascular state space representations, enabling consistent modeling of vascular structures across multiple modalities. Extensive experiments on various angiographic datasets demonstrate the superiority of VasTSD over prior works, achieving enhanced continuity of blood vessels in synthesized angiographic synthesis for multiple modalities and anatomical regions.
title VasTSD: Learning 3D Vascular Tree-state Space Diffusion Model for Angiography Synthesis
topic Computer Vision and Pattern Recognition
Image and Video Processing
url https://arxiv.org/abs/2503.12758