Image-Based Metrics in Ultrasound for Estimation of Global Speed-of-Sound

Fuente: arXiv
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Main Authors: Denkin, Roman, Goksel, Orcun
Format: Preprint
Published: 2025
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author Denkin, Roman
Goksel, Orcun
author_facet Denkin, Roman
Goksel, Orcun
contents Accurate speed-of-sound (SoS) estimation is crucial for ultrasound image formation, yet conventional systems often rely on an assumed value for imaging. We propose to leverage conventional image analysis techniques and metrics as a novel and simple approach to estimate tissue SoS. We study eleven metrics in three categories for assessing image quality, image similarity and multi-frame variation, by testing them in numerical simulations and phantom experiments, as well as testing in an in vivo scenario. Among single-frame image quality metrics, conventional Focus and a proposed metric variation on Tenengrad present satisfactory accuracy (5-8\,m/s on phantoms), but only when the metrics are applied after compounding multiple frames. Differential image comparison metrics were more successful overall with errors consistently under 8\,m/s even applied on a single pair of frames. Mutual information and correlation metrics were found to be robust in processing relatively small image patches, making them suitable for focal estimation. We present an in vivo study on breast density classification based on SoS, to showcase clinical applicability. The studied metrics do not require access to raw channel data as they can operate on post-beamformed and/or B-mode data. These image-based methods offer a computationally efficient and data-accessible alternative to existing physics- and model-based approaches for SoS estimation.
format Preprint
id arxiv_https___arxiv_org_abs_2503_14094
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Image-Based Metrics in Ultrasound for Estimation of Global Speed-of-Sound
Denkin, Roman
Goksel, Orcun
Image and Video Processing
Computer Vision and Pattern Recognition
Medical Physics
Accurate speed-of-sound (SoS) estimation is crucial for ultrasound image formation, yet conventional systems often rely on an assumed value for imaging. We propose to leverage conventional image analysis techniques and metrics as a novel and simple approach to estimate tissue SoS. We study eleven metrics in three categories for assessing image quality, image similarity and multi-frame variation, by testing them in numerical simulations and phantom experiments, as well as testing in an in vivo scenario. Among single-frame image quality metrics, conventional Focus and a proposed metric variation on Tenengrad present satisfactory accuracy (5-8\,m/s on phantoms), but only when the metrics are applied after compounding multiple frames. Differential image comparison metrics were more successful overall with errors consistently under 8\,m/s even applied on a single pair of frames. Mutual information and correlation metrics were found to be robust in processing relatively small image patches, making them suitable for focal estimation. We present an in vivo study on breast density classification based on SoS, to showcase clinical applicability. The studied metrics do not require access to raw channel data as they can operate on post-beamformed and/or B-mode data. These image-based methods offer a computationally efficient and data-accessible alternative to existing physics- and model-based approaches for SoS estimation.
title Image-Based Metrics in Ultrasound for Estimation of Global Speed-of-Sound
topic Image and Video Processing
Computer Vision and Pattern Recognition
Medical Physics
url https://arxiv.org/abs/2503.14094