Improving PET scanner time-of-flight resolution using additional prompt photon

Fuente: arXiv
Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Raczynski, Lech, Krzemien, Wojciech, Klimaszewski, Konrad
Format: Preprint
Veröffentlicht: 2025
Schlagworte:
Online-Zugang:
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
_version_ 1866913979549351936
author Raczynski, Lech
Krzemien, Wojciech
Klimaszewski, Konrad
author_facet Raczynski, Lech
Krzemien, Wojciech
Klimaszewski, Konrad
contents Positronium Imaging requires two classes of events: double-coincidences originated from pair of back-to-back annihilation photons and triple-coincidences comprised with two annihilation photons and one additional prompt photon. The standard reconstruction of the emission position along the line-of-response of triple-coincidence event is the same as in the case of double-coincidence event; an information introduced by the high-energetic prompt photon is ignored. In this study, we propose to extend the reconstruction of position of triple-coincidence event by taking into account the time and position of prompt photon. We incorporate the knowledge about the positronium lifetime distribution and discuss the limitations of the method based on the simulation data. We highlight that the uncertainty of the estimate provided by prompt photon alone is much higher than the standard deviation estimated based on two annihilation photons. We finally demonstrate the extent of resolution improvement that can be obtained when estimated using three photons.
format Preprint
id arxiv_https___arxiv_org_abs_2503_15153
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Improving PET scanner time-of-flight resolution using additional prompt photon
Raczynski, Lech
Krzemien, Wojciech
Klimaszewski, Konrad
Medical Physics
Instrumentation and Detectors
Positronium Imaging requires two classes of events: double-coincidences originated from pair of back-to-back annihilation photons and triple-coincidences comprised with two annihilation photons and one additional prompt photon. The standard reconstruction of the emission position along the line-of-response of triple-coincidence event is the same as in the case of double-coincidence event; an information introduced by the high-energetic prompt photon is ignored. In this study, we propose to extend the reconstruction of position of triple-coincidence event by taking into account the time and position of prompt photon. We incorporate the knowledge about the positronium lifetime distribution and discuss the limitations of the method based on the simulation data. We highlight that the uncertainty of the estimate provided by prompt photon alone is much higher than the standard deviation estimated based on two annihilation photons. We finally demonstrate the extent of resolution improvement that can be obtained when estimated using three photons.
title Improving PET scanner time-of-flight resolution using additional prompt photon
topic Medical Physics
Instrumentation and Detectors
url https://arxiv.org/abs/2503.15153