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Main Authors: Zhou, Anni, Beyah, Raheem, Kamaleswaran, Rishikesan
Format: Preprint
Published: 2025
Subjects:
Online Access:https://arxiv.org/abs/2503.16708
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author Zhou, Anni
Beyah, Raheem
Kamaleswaran, Rishikesan
author_facet Zhou, Anni
Beyah, Raheem
Kamaleswaran, Rishikesan
contents In critical care settings, timely and accurate predictions can significantly impact patient outcomes, especially for conditions like sepsis, where early intervention is crucial. We aim to model patient-specific reward functions in a contextual multi-armed bandit setting. The goal is to leverage patient-specific clinical features to optimize decision-making under uncertainty. This paper proposes NeuroSep-CP-LCB, a novel integration of neural networks with contextual bandits and conformal prediction tailored for early sepsis detection. Unlike the algorithm pool selection problem in the previous paper, where the primary focus was identifying the most suitable pre-trained model for prediction tasks, this work directly models the reward function using a neural network, allowing for personalized and adaptive decision-making. Combining the representational power of neural networks with the robustness of conformal prediction intervals, this framework explicitly accounts for uncertainty in offline data distributions and provides actionable confidence bounds on predictions.
format Preprint
id arxiv_https___arxiv_org_abs_2503_16708
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle NeuroSep-CP-LCB: A Deep Learning-based Contextual Multi-armed Bandit Algorithm with Uncertainty Quantification for Early Sepsis Prediction
Zhou, Anni
Beyah, Raheem
Kamaleswaran, Rishikesan
Machine Learning
In critical care settings, timely and accurate predictions can significantly impact patient outcomes, especially for conditions like sepsis, where early intervention is crucial. We aim to model patient-specific reward functions in a contextual multi-armed bandit setting. The goal is to leverage patient-specific clinical features to optimize decision-making under uncertainty. This paper proposes NeuroSep-CP-LCB, a novel integration of neural networks with contextual bandits and conformal prediction tailored for early sepsis detection. Unlike the algorithm pool selection problem in the previous paper, where the primary focus was identifying the most suitable pre-trained model for prediction tasks, this work directly models the reward function using a neural network, allowing for personalized and adaptive decision-making. Combining the representational power of neural networks with the robustness of conformal prediction intervals, this framework explicitly accounts for uncertainty in offline data distributions and provides actionable confidence bounds on predictions.
title NeuroSep-CP-LCB: A Deep Learning-based Contextual Multi-armed Bandit Algorithm with Uncertainty Quantification for Early Sepsis Prediction
topic Machine Learning
url https://arxiv.org/abs/2503.16708